Evaluation of the Liver for Metastatic Disease

Paulson, Erik K.

doi:10.1055/s-2001-15498

Cited by 37 publications

(23 citation statements)

References 46 publications

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“…Recognition of a hypoechoic halo or rim surrounding an echogenic or isoechoic liver mass, suggested probable malignancy, this was also been mentioned in previous studies [52,53] and masses with this morphologic characteristic were provoked confirmatory imaging with computed tomographic (CT) scans ,some showed similar findings and another showed different results as presented in table (7) .Multiple hypoechoic masses in the liver most often suggest metastases. [54]This was seen in our results and it was also diagnosed well in the contrast enhanced CT scans. By comparison, the common appearance of abdomino pelvic mass was diagnosed ultrasonographically with good evaluation of adenexia, it was found as a solid, uniformly echogenic mass, possibly showing increased enhancement deep to the mass, is so well recognized in (1(2%) of the patients with hepatocellular carcinoma (HCC) and 1(2%) of the cases affected with metastases, the identification of such a mass rule out the need for CT imaging where the diagnoses was done regarding to its findings, similar results were reported in previous study.…”

Section: Discussionsupporting

confidence: 74%

Diagnostic Performance of Imaging in Detection and Characterization of Liver Lesions

Osman¹,

Ayad²

2017

IOSR JDMS

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Section: Discussionsupporting

confidence: 74%

Diagnostic Performance of Imaging in Detection and Characterization of Liver Lesions

Osman¹,

Ayad²

2017

IOSR JDMS

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“…The sensitivity of pre-operative imaging studies has improved up to 60e75% with spiral CT and 80e85% with MR [1], but the combination of diagnostic laparoscopy and intra-operative ultrasound (LIOUS) has achieved 90e96% accuracy in the staging of liver and pancreatic malignancies. This allows patients who are not candidates for curative surgery to be spared the ordeal of laparotomy [2e4].…”

Section: Introductionmentioning

confidence: 99%

Laparoscopic intra-operative ultrasound in liver and pancreas resection: Analysis of 93 cases

Piccolboni

Ciccone

Settembre

et al. 2010

Journal of Ultrasound

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KEYWORDSLiver surgery; Pancreas surgery; Laparoscopic ultrasound.Abstract Introduction: Laparoscopic inspection before pancreatic and liver surgery is a widely accepted approach and has changed the surgical strategy in a growing number of patients for the last 10 years. The addition of intra-operative ultrasound to laparoscopy has further refined surgical judgments. The aim of this study was to evaluate the impact of open (IOUS) or laparoscopic (LIOUS) ultrasound in patients undergoing hepatic or pancreatic resection for benign or malignant lesions. Materials and methods: In the years 2005e2008, 45 patients (aged 42e75 years) were selected for liver resection, and 48 others (aged 14e72 years) were selected for partial pancreatic resection. Intra-operative ultrasound was performed for surgical staging. An Aloka SSD-5500 scanner (Aloka, Tokyo, Japan) was used with a flexible laparoscopic multifrequency linear and an electronic T-shaped linear probe. Results: LIOUS prevented useless laparotomies in six patients (13.3%) with liver tumors and, coupled with IOUS, revealed previously undetected tumors that required a change in the surgical strategy in 5 others (11.1%). In patients with pancreatic disease, LIOUS excluded the possibility of radical surgery in 7 patients (14.4%) due to the presence of mesenteric vein infiltration, involvement of the celiac or para-aortic nodes, or the presence of liver or peritoneal micro-metastases. In 11 patients with benign lesions, it defined the lesions' relation to the Wirsung duct and splenic vessels, and in 6 others it provided guidance for aspiration of fluid for chemical and cytologic analysis. Conclusions: LIUOS and IOUS can play fundamental roles in selecting patients for resective surgery and in planning the surgical approach. They provided information that affected surgical strategies in 11 patients with liver disease (24.4%) and 13 with pancreas disease (27%).Sommario Introduzione: L'ispezione laparoscopica in chirurgia del pancreas o del fegato è un approccio ampiamente utilizzato. L'aggiunta dell'ecografia intra-operatoria alla laparoscopia ha di recente ulteriormente migliorato la valutazione chirurgica. Lo scopo di questo studio è stato di valutare l'impatto dell'ecografia intra-operatoria open (IOUS) o laparoscopica (LIOUS) in chirurgia del fegato e del pancreas. pancreas. L'ecografia intra-operatoria è stata effettuata per mezzo di un apparecchio Aloka SSD-550 (Aloka, Tokyo, Giappone), con sonda lineare laparoscopica a punta flessibile e sonda elettronica lineare a T. Risultati: Tra i pazienti epatici, la LIOUS ha evitato inutili laparotomie in sei pazienti (13,3%) ed, insieme alla IOUS, ha consentito di trovare noduli non diagnosticati ed ha cambiato la strategia chirurgica in cinque pazienti (11,1%). Nel gruppo pancreas, la LIOUS ha escluso 7 pazienti (14,4%) dalla chirurgia radicale, per infiltrazione della vena mesenterica, coinvolgimento dei linfonodi celici o para-aortici, micro-metastasi epatiche e peritoneali. In 11 lesioni benigne, ha consentito la definizion...

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“…Chest radiography is insensitive in detecting mediastinal and hilar lymphadenopathies because of structure overlapping and inadequate soft-tissue contrast. Ultrasonography can visualize superficial hepatic structures well; however, this technique is relatively operator-dependent and has inherent problems in differentiating between benign and metastatic tumors (7). Finally, skeletal scintigraphy appears to be insensitive for detecting early bone or bone marrow metastasis (8).…”

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confidence: 99%

18F-FDG PET Can Replace Conventional Work-up in Primary M Staging of Nonkeratinizing Nasopharyngeal Carcinoma

Liu¹,

Lin²,

Chang³

et al. 2007

Journal of Nuclear Medicine

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Conventional work-up (CWU) with chest radiography, abdominal ultrasonography, and skeletal scintigraphy has limited value in M staging of nonkeratinizing nasopharyngeal carcinoma (NPC). Our aim was to evaluate whether 18 F-FDG PET could replace CWU by comparing their diagnostic efficacies. Methods: Patients with histologically proven nonkeratinizing NPC and no prior treatment were prospectively enrolled. All study participants underwent CWU and 18 F-FDG PET for primary M staging. Distant metastasis was considered to be present if there was any reliable evidence identified within 1 y after diagnosis. The comparative diagnostic efficacies of 18 F-FDG PET, CWU, and the combination of 18 F-FDG PET and CWU (PET1CWU) were evaluated using the areas under the receiver-operating-characteristic (ROC) curves. Results: Sixty-one (20.3%) of 300 eligible patients were found to have distant metastases. On a patient-based analysis, 18 F-FDG PET was found to be more effective than CWU (P , 0.001), whereas it was equally effective with PET1CWU (P 5 0.130). On region-based analyses, 18 F-FDG PET was more effective than skeletal scintigraphy and chest radiography for detecting bone metastases (P , 0.001) and chest metastases (P , 0.001), respectively. 18 F-FDG PET and abdominal ultrasound were equally effective for detecting hepatic metastases (P 5 0.127). On region-based analyses, the combination of 18 F-FDG PET and CWU did not yield any noticeable increase in diagnostic efficacy. Conclusion: 18 F-FDG PET can replace CWU in primary M staging of nonkeratinizing NPC.

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Evaluation of the Liver for Metastatic Disease

Cited by 37 publications

References 46 publications

Diagnostic Performance of Imaging in Detection and Characterization of Liver Lesions

Diagnostic Performance of Imaging in Detection and Characterization of Liver Lesions

Laparoscopic intra-operative ultrasound in liver and pancreas resection: Analysis of 93 cases

18F-FDG PET Can Replace Conventional Work-up in Primary M Staging of Nonkeratinizing Nasopharyngeal Carcinoma

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