Evaluation of the health impact of lowering the formaldehyde occupational exposure limit for Quebec workers

Noisel, Nolwenn; Bouchard, Michèle; Carrier, Gaétan

doi:10.1016/j.yrtph.2007.02.001

Cited by 41 publications

(23 citation statements)

References 34 publications

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“…Human studies have shown that chronic inhalation exposure to formaldehyde is associated with respiratory symptoms and eye, nose and throat irritation [14,44] . On the other hand, the oral exposure to formaldehyde related to the induction of gastrointestinal tract ulcer.…”

Section: Health Effect To Humanmentioning

confidence: 99%

The Health Risk of Formaldehyde to Human Beings

Norliana¹,

Abdulamir²,

Bakar³

et al. 2009

American J. of Pharmacology and Toxicology

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Problem statement: Formaldehyde was classified as a potential human carcinogen, identified by the US Environmental Protection Agency and International Agency for Research on Cancer as a Class 2A carcinogen. It also can cause irritation to human. However, formaldehyde present in biological fluids or tissues and environment as a result of natural processes or from man-made sources and can be emitted slowly into the air. Formaldehyde was used in many industries, hospitals and research as a sterilizing and preserving agent. The utmost concern of this study was about the present of formaldehyde in seafood product. Approach: A review was done on the health effect adverse by formaldehyde, formaldehyde toxicity to human, formaldehyde in seafood and methods to control formaldehyde in food and seafood. Google, Pubmed, Science Direct and Scopus were used in preparation of this review. Results: This review clarified that one of the formaldehyde source to human was seafood. Previous study showed that seafood contained high amount of formaldehyde because of natural production by postmortem enzymatic reaction besides the used of formaldehyde as preservative. Based on prior studies, exposure to formaldehyde can cause irritation and genotoxicity effect. For cancer effect studies, formaldehyde was long considered as a potential human carcinogen based on experimental animal studies and limited evidence of human carcinogenicity. Conclusion: Several mefinding of many health effect of formaldehyde, suggests that the investigation of level of formaldehyde in seafthods have been suggested to reduce formaldehyde in food such as cooking and washing. The ood should be done and also the level of formaldehyde natural production.

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Section: Health Effect To Humanmentioning

confidence: 99%

The Health Risk of Formaldehyde to Human Beings

Norliana¹,

Abdulamir²,

Bakar³

et al. 2009

American J. of Pharmacology and Toxicology

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“…Interests in carbonyls continue to attract atmospheric chemists due to the carbonyls' important roles in atmospheric photochemistry (Carlier et al, 1986;Vairavamurthy et al, 1992;Atkinson, 2000) and negative impacts on human health (Timmons et al, 2002;Noisel et al, 2007). Studies have been performed to evaluate carbonyls' levels and sources (Kean et al, 2001;Seco et al, 2007;Pal et al, 2008), distributions (Moussa et al, 2006;Cerón et al, 2007;Pang et al, 2009), photochemical formations (Wiedinmyer et al, 2001;Duane et al, 2002;Guo et al, 2013), health risks (Cavalcante et al, 2006;Noisel et al, 2007;Weng et al, 2009), and analytical approaches (Guo et al, 2007;Kim and Pal, 2010;Ho et al, 2011;Pang et al, 2011;Saha et al, 2012;Xie et al, 2013).…”

Section: Introductionmentioning

confidence: 99%

“…Studies have been performed to evaluate carbonyls' levels and sources (Kean et al, 2001;Seco et al, 2007;Pal et al, 2008), distributions (Moussa et al, 2006;Cerón et al, 2007;Pang et al, 2009), photochemical formations (Wiedinmyer et al, 2001;Duane et al, 2002;Guo et al, 2013), health risks (Cavalcante et al, 2006;Noisel et al, 2007;Weng et al, 2009), and analytical approaches (Guo et al, 2007;Kim and Pal, 2010;Ho et al, 2011;Pang et al, 2011;Saha et al, 2012;Xie et al, 2013). However in China, investigation on carbonyls in developing regions (e.g., in Guangxi) is very limited due to the poor economic capabilities compared to economically developed regions (Feng et al, 2005;Duan et al, 2008;Lü et al, 2010;Guo et al, 2011;Zhang et al, 2012), resulting in that our current knowledge of carbonyls remains weak in these developing regions.…”

Section: Introductionmentioning

confidence: 99%

Seasonal and Diurnal Characteristics of Carbonyls in Urban Air in Qinzhou, China

Guo

Chen

et al. 2014

Aerosol Air Qual. Res.

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Ambient carbonyls in urban air in Qinzhou were studied form October 2011 to July 2012 to investigate their distribution characteristics and sources. Acetaldehyde (8.04 ± 9.00 µg/m 3 ), formaldehyde (6.70 ± 6.36 µg/m 3 ) and acetone (2.43 ± 2.81 µg/m 3 ) were three most abundant carbonyls, accounting for ~90% of the seven carbonyls identified. Concentrations of most carbonyls showed significantly higher levels in spring and summer than those in autumn and winter. Seasonal and diurnal variations indicated that formaldehyde and acetaldehyde were related to barbecue emissions and photochemical loss, while solvent usage was responsible for acetone. The average C 1 /C 2 ratio was higher (1.92) in summer than that during other seasons (0.52-1.78), implying the positive impact of photochemical loss or formation; and a significantly lower C 2 /C 3 ratio (2.57) was observed in winter than during other seasons (12.47-52.82), suggesting significant emissions from straw burning and barbecues. Formaldehyde and acetaldehyde were the two major contributors (63-97%) to O 3 formation, particularly in spring and summer.

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“…Dentre os resíduos químicos de maior geração em instituições de saúde, estão o formaldeído (ou formol), os isômeros xilenos (ou xilol) e o glutaraldeído [2]. O formaldeídoé um reagente químico grandemente utilizado na produção de diversos produtos [3], [4].É um intermediário químico utilizado em vários campos das ciências da saúde [5] incluindo os produtos farmacêuticos, e também em produtos de limpeza, conservação de peças anatômica e cadáveres [6]. Embora muitos estudos demonstrem sua toxicidade para os seres humanos e ao meio ambiente e seu custo seja relativamente alto [5], o formaldeídoé utilizado por grande parte dos estabelecimentos de saúde por ser um método tradicional de preservação de tecidos com resultados satisfatórios [7].…”

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Environmental waste management in a School Hospital and in a Laboratory of Human Anatomy of a University

Manfredini¹,

Filho²,

Schneider³

2013

Sci. cum Ind.

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ResumoAs atividades científicas e profissionais desenvolvidas em um Hospital Escola e em um Laboratório de Anatomia Humana de uma universidade podem gerar, paralelamente, resíduos químicos de diversos graus de periculosidade, que necessitam de tratamento físico e/ou químico adequado, antes de serem enviados ao destino final. O Hospital Geral (HG) gera mensalmente 10 litros de xilenos e 50 litros de glutaraldeído para prestar a assistência a seus pacientes. Já o Laboratório de Anatomia Humana da Universidade de Caxias do Sul (LA-UCS) usa mais de 10 mil litros para a conservação de cadáveres em tanques. O estudo propõe a analisar o gerenciamento de resíduos químicos deste HG e do LA-UCS e propor técnicas de recuperação e reutilização dos compostos químicos formaldeído, xilenos e glutaraldeído, minimizando assim os impactos gerados pelo uso. Até o presente momento foram coletadas duas séries de amostras (em março e abril de 2013) de xilol, glutaraldeído e formol no HG e também no LA-UCS e pretende-se repetir as coletas com periodicidade mensal, nos próximos dois semestres. Os resultados parciais mostram que, comparando as relações deárea e asáreas cromatográficas médias (em µV.s) dos padrões cromatográficos com os compostos de interesse, houve um aumento no percentual do formol das amostras em relação ao formol padrão (121,84%), o que pode ser devidoà contaminação do mesmo, com compostos orgânicos com tempo de retenção próximos ao composto de interesse; no xilol houve pouca degradação nas amostras, indicando que este composto pode ser reaproveitado nos procedimentos comuns das instituições de saúde; em relação ao glutaraldeído foi observada uma importante degradação pois o composto nas amostras representa apenas 61,88% daárea do pico cromatográfico do padrão, portanto o reúso destes compostos pode exigir o emprego de métodos de purificação, tais como destilação simples e destilação fracionada. Palavras-chaveResíduos químicos, Gerenciamento, Reúso. Environmental Waste Management in a SchoolHospital and in a Laboratory of Human Anatomy of a University AbstractThe scientific and professional activities developed in a Hospital School and a Laboratory of Human Anatomy of a university can generate parallel, chemical residues from various degrees of dangerousness, which may require physical treatment and / or suitable chemical, before being sent to final destination. The General Hospital (GH) generates monthly 10 L of xylenes and 50 L of glutaraldehyde to provide ass instance to their patients. Already the Laboratory of Human Anatomy of University de Caxias do Sul (AL-UCS) uses more than 10,000 liters for preserving corpses in tanks. The present study aims to analyze the chemical waste management of the GH and the AL-UCS and propose techniques for recovery and reuse of chemicals formaldehyde, glutaraldehyde and xylenes, minimizing the impacts generated by the use, often indispensable and sometimes questionable, of such waste. So far two sets of samples were collected (in March and April 2013) of xylene, glutaraldehyde and...

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Evaluation of the health impact of lowering the formaldehyde occupational exposure limit for Quebec workers

Cited by 41 publications

References 34 publications

The Health Risk of Formaldehyde to Human Beings

The Health Risk of Formaldehyde to Human Beings

Seasonal and Diurnal Characteristics of Carbonyls in Urban Air in Qinzhou, China

Environmental waste management in a School Hospital and in a Laboratory of Human Anatomy of a University

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