Evaluation of the fourth ventricle and nomogram of intracranial translucency at 11–13 weeks of gestation

Abstract

Objective: The aim of this study was to evaluate normal reference ranges of intracranial translucency (IT) diameter, and to obtain its nomogram in normal fetuses, during 11-13 weeks of gestation.Methods: This was a retrospective data evaluation of first trimester ultrasound scans. A total of 2417 singleton pregnancies were included in the study. IT was measured in the nuchal translucency plane. Nomogram and formula of IT diameter were defined according to crown-rump length (CRL). Results:The IT diameters were measured successfully in 2250 fetuses (93.1%). The mean maternal age was 31.8±4.0 years. The mean CRL was 62.0±6.9 mm. The mean IT diameter was 1.83±0.29 mm. The linear tendency was determined according to the following formula: IT (mm)= 0.54 + 0.02 × CRL (mm); r 2 =0.24. Conclusion:We presented the feasibility and a nomogram of IT diameter at 11 to 13 +6 weeks of gestation in our population to be used for early prediction of neural tube defects.

Failure of getting intracranial translucency image in posterior fossa in the examination of singleton pregnancies at 11–13 weeks of gestation: reasons and outcomes

“…[9] We carried out some preliminary studies on IT presence in the previous years and generated some nomograms by the weeks of gestation. [14][15][16] In our present study, we aimed to investigate the reasons and outcomes of being unable to see intracranial translucency (IT), and to determine the sensitivity, specificity, positive and negative predictive values and our diagnostic accuracy rate for the poor outcomes that may follow IT negativity by extending our current series slightly further.…”

Tekiz gebeliklerde birinci trimester intrakranial translusensi nomogramı

“…IT'nin normal nomogramının belirlenmesi bu açıdan önemlidir. Türk toplumu için yapılan sınırlı sayıda çalışma vardır [15,16]. Bu çalışmadaki primer amacımız IT için normal sınır değerleri açısından faydalı olması amaçlanmıştır.…”

“…Aydın ve ark. çalışmalarında 2250 fetüs değerlendirilmiş, ortalama CRL=62.0±6,9 ve IT=1,83±0,29 olarak hesaplanmıştır [15]. Kose ve ark.…”