Evaluation of the fitness benefit conferred by RNA cis-regulators toStreptococcus pneumoniaeduring infection
Indu Warrier,
Ariana Perry,
Sara M. Hubbell
et al.
Abstract:Bacteria have evolved complex transcriptional regulatory networks, as well as many diverse regulatory strategies at the RNA level, to enable more efficient use of metabolic resources and rapid response to changing conditions. However, most RNA-based regulatory mechanisms are not well conserved across different bacterial species despite controlling genes important for virulence or essential biosynthetic processes. Here, we characterize the activity of, and assess the fitness benefit conferred by, twelve cis-act… Show more
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