Evaluation of the efficacy of multiple physical, biological and natural antimicrobial interventions for control of pathogenic Escherichia coli on beef

Stratakos, Alexandros Ch.; Grant, Irene R.

doi:10.1016/j.fm.2018.05.011

Cited by 49 publications

(30 citation statements)

References 65 publications

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“…Although the used concentrations of lactic and acetic acids showed a great antibacterial effect, they have no adverse effect on the sensory and organoleptic examinations of the carcass's meat. This character was previously reported by (Stratakos and Grant, 2018) where they reported that, the diluted solutions of organic acids (1 to 3%) are generally don't affect the wholesome organoleptic properties of fresh meat when used as a carcass decontaminant. In addition, this study recorded that lactic acid showed greater inhibitory effect than acetic acid in the same concentrations.…”

Section: Discussionsupporting

confidence: 67%

Efficiency of some organic acids as decontaminants in sheep carcasses

ellatif¹,

Saad

Hassanin

et al. 2020

Benha Veterinary Medical Journal

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Potent and food-safe antibacterial chemicals capable of decontaminating carcass surfaces have been researched for a long time due to their great value for the quality and shelf life of the meat. The aim of current study is to test the antibacterial effect of lactic acid (LA) and acetic acid (AA) spray treatments using three concentrations (1, 1.5 and 2 %) on the aerobic plate count, Enterobacteriacae count, coliform count, and Staphylococcus count of fresh sheep carcasses surface after 20 minutes of spraying. Results of the investigated bacteriological parameters showed significant reductions after being exposed to organic acids, especially Gram-negative bacteria (Enterobacteriacae) which showed greater sensitivity to the used organic acids than Gram positive bacteria (Staphylococcus), where greater concentration gave greater reduction in the bacterial counts. Moreover, spray wash of lactic acid resulted in higher reduction of bacterial counts on meat surface than acetic acid. From the obtained results, organic acids showed safe, simple, efficient, cheap, and highly effective modality of meat decontamination, on addition, application of lactic acid 2.0% spray showed higher anti-bacterial effect, therefore, it is recommended to improve safety of sheep carcasses for industrial scales.

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Section: Discussionsupporting

confidence: 67%

Efficiency of some organic acids as decontaminants in sheep carcasses

ellatif¹,

Saad

Hassanin

et al. 2020

Benha Veterinary Medical Journal

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“…Combinations of natural antimicrobials, similar to AuraShield L (e.g. Auranta 3001), were previously described as efficient in preventing bacterial infections in chicken and mouse animal models [13][14][15][16] . These results show that Auranta 3001 has a negative impact on the expression of virulence genes in Campylobacter spp.…”

mentioning

confidence: 99%

Antiviral activity of a novel mixture of natural antimicrobials, in vitro, and in a chicken infection model in vivo

Balta

Ştef

Peţ

et al. 2020

Sci Rep

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The aim of this study was to test in vitro the ability of a mixture of citrus extract, maltodextrin, sodium chloride, lactic acid and citric acid (AuraShield L) to inhibit the virulence of infectious bronchitis, Newcastle disease, avian influenza, porcine reproductive and respiratory syndrome (PRRS) and bovine coronavirus viruses. Secondly, in vivo, we have investigated its efficacy against infectious bronchitis using a broiler infection model. In vitro, these antimicrobials had expressed antiviral activity against all five viruses through all phases of the infection process of the host cells. In vivo, the antimicrobial mixture reduced the virus load in the tracheal and lung tissue and significantly reduced the clinical signs of infection and the mortality rate in the experimental group E2 receiving AuraShield L. All these effects were accompanied by a significant reduction in the levels of pro-inflammatory cytokines and an increase in IgA levels and short chain fatty acids (SCFAs) in both trachea and lungs. Our study demonstrated that mixtures of natural antimicrobials, such AuraShield L, can prevent in vitro viral infection of cell cultures. Secondly, in vivo, the efficiency of vaccination was improved by preventing secondary viral infections through a mechanism involving significant increases in SCFA production and increased IgA levels. As a consequence the clinical signs of secondary infections were significantly reduced resulting in recovered production performance and lower mortality rates in the experimental group E2.

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“…The anti-virulent effect of natural antimicrobial mixtures was previously described in other pathogens e.g., Campylobacter jejuni, Campylobacter coli and Shiga Toxin Producing E. Coli (STEC) [13,41]. This anti-virulent effect was exhibited by decreasing the activity of major virulence factors including motility, and by reducing the in vitro and in vivo infection abilities, T6SS and biofilm formation [13,42].…”

Section: Discussionmentioning

confidence: 84%

Attenuation of Vibrio parahaemolyticus Virulence Factors by a Mixture of Natural Antimicrobials

et al. 2019

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Reducing acute mortality in aquatic crustaceans using natural alternatives to antibiotics has become a necessity, firstly for its positive impact on the aquaculture industry and, secondly, because the extensive use of antibiotics may lead to increased levels of drug resistance in pathogenic microorganisms. This study aimed to investigate the effect of a mixture of natural antimicrobials on the in vitro and in vivo virulence abilities of Type VI secretion system (T6SS)-positive Vibrio parahaemolyticus (A3 and D4), strains known as having potentially harmful health consequences for aquatic crustaceans and consumers. Herein, we report that a natural antimicrobial mixture (A3009) was capable of significantly reducing the virulence of V. parahaemolyticus strains A3 and D4 in an in vitro infection model, using the fish cell line CHSE-214, an effect which correlates with the bacterial downregulation of hcp1 and hcp2 gene expression and with the ability of the antimicrobial to efficiently retain low cytotoxic levels (p < 0.001). We show for the first time that a natural antimicrobial is able to significantly reduce the mortality of shrimps in a challenge experiment and is able to significantly attenuate H 2 O 2 release during infection (p < 0.001), indicating that it could harbor positive intestinal redox balance effects.

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Evaluation of the efficacy of multiple physical, biological and natural antimicrobial interventions for control of pathogenic Escherichia coli on beef

Cited by 49 publications

References 65 publications

Efficiency of some organic acids as decontaminants in sheep carcasses

Efficiency of some organic acids as decontaminants in sheep carcasses

Antiviral activity of a novel mixture of natural antimicrobials, in vitro, and in a chicken infection model in vivo

Attenuation of Vibrio parahaemolyticus Virulence Factors by a Mixture of Natural Antimicrobials

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