Evaluation of the Efficacy of Herbal Antidotes of Viper Snakes through In-silico Docking Analysis of their Bioactive Components Targeting Phospholipase A2
Abstract:Introduction: Snake bite is common in Rural areas. Many toxic snakes produce neurotoxic, Myotoxic, and hemotoxic effects. Snake venom is rich in metalloproteinases and Phospholipases. PhospholipaseA2 accounts for most of the toxic effects of Viper snakes. Many herbal antidotes have been in practice in the Siddha system which lacks scientific evidence.
Aim: This study aims to rule out the Binding pose and affinity of bioactive components derived from certain herbs with the target by forming hydrogen bonds… Show more
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