Evaluation of the efficacy of antibiotics in the treatment of Staphylococcus aureus isolated from clinical cases in Al-Dawwaniyah hospitals

Abstract

Staphylococcus aureus, especially resistant to methicillin, is one of the Basic causes of hospital infection, its resistance to antibiotics has constituted a public health problem worldwide, due to the lack of studies related to the examination of sensitivity to antibiotics, especially in methicillin-resistant species in Iraq and in the city of Diwaniyah in particular. Therefore,The current study aimed to find out the prevalence rate antibiotic resistance in these bacteria isolated from different clinical sources in some hospitals in the governorate. During the research, 554 clinical samples (221 urine samples, 178 sputum samples, 100 burns samples and 55 injuries) for the period from the 11th of 2021 to the 3rd of 2022. Relying on the results of in vitro culture and conventional microscopic and biochemical assays, 100 isolates of Staphylococcus aureus were identified, using the cefoxetine disc spread method, as 80 isolates belong to MRSA. The results of the antibiotic susceptibility test were examined retrospectively. Using the method (Kirby Bauer) using 20 antibiotics used in the current study and it was found that (78%) Of these bacteria were multidrug resistant (MDR).