Evaluation of the efficacy of a haemostatic matrix for control of intraoperative and postoperative bleeding in major lung surgery: a prospective randomized study

Abstract

In conclusion, the application of Floseal® in major lung resections proved safe and effective in increasing the intraoperative successful haemostasis rate and in reducing postoperative variation in haemoglobin and haematocrit levels. The sealant use was also related with a significantly shorter chest drain duration and hospitalization.

Estimated intraoperative blood loss correlates with postoperative cardiopulmonary complications and length of stay in patients undergoing video-assisted thoracoscopic lung cancer lobectomy: a retrospective cohort study

“…In general, thoracic surgeons regard an adequate hemostasis as the fundamental for the final success of lung cancer surgery due to the need to perform SMLND and the presence of scar tissues or adhesions following neoadjuvant therapy [ 25 ]. In addition, a larger volume of EIBL is also considered as an effective indicator for poor oncological outcomes, suggesting that thoracic surgeons should try their best to achieve the ‘bloodless’ goal [ 26 ].…”

“…According to our study results, effective control of intraoperative bleeding still remains one of the paramount issues that must be judiciously considered in lung cancer surgery. Therefore, in order to inhibit the stress responses and enhance the postoperative recovery, thoracic surgeons should make more efforts to achieve a ‘bloodless’ goal through more meticulous surgical techniques, which represent the primary approach for intraoperative bleeding control [ 25 ].…”

Postoperative cytological findings from the use of the Integran microfibrillar collagen hemostatic matrix in conization

“…In recent years, the decrease in the antigenicity of hemostatic agents has allowed their efficient use during surgery in many countries . In gynecology, the gelatin‐type hemostatic matrix Floseal has been described in several reports of its use for myomectomy for fibroids and a laparoscopic therapy for an ectopic pregnancy .…”

Cytologic findings following intraoperative use of FlosealR hemostatic matrix: A potential diagnostic pitfall in fluid aspiration cytology

“…Its efficacy has been reported in numerous studies [1][2][3][4][5] with rare reports of adverse side effects such as anaphylactic reactions 6 and acute cerebral edema 7 following intraoperative application. It has widespread use in surgery as an aid in intraoperative hemostasis of bleeding sites.…”

“…It has widespread use in surgery as an aid in intraoperative hemostasis of bleeding sites. Its efficacy has been reported in numerous studies [1][2][3][4][5] with rare reports of adverse side effects such as anaphylactic reactions 6 and acute cerebral edema 7 following intraoperative application. Its utility in the management of a number of conditions such as epistaxis, 8 ectopic pregnancy, [9][10][11][12] and intractable hematuria 13 has also been described.…”