Evaluation of the Effects of Opium on the Expression of SOX2 and OCT4 in Wistar Rat Bladder
Iman Menbari Oskouie,
Leila Zareian Baghdadabad,
Rahil Mashhadi
et al.
Abstract:BACKGROUND: Bladder cancer is a malignancy greatly affected by behavioral habits. The aim of this study was to examine the effect of opium on changes in the expression of OCT4 and SOX2 in the bladder tissue of rats. METHOD: Thirty six rats were divided into six groups: 24 rats in the addicted group received morphine and opium for 4 months with 12 rats in the control group. Blood testing was done for the evaluation of CBC, MDA, and TAC. The bladder tissue was removed and checked by histopathological examination… Show more
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