Evaluation of the Effects of Particle Sizes of Silver Nanoparticles on Various Biological Systems

Kong, In Chul; Ko, Kyung‐Seok; Koh, Dong‐Chan

doi:10.3390/ijms21228465

Cited by 22 publications

(11 citation statements)

References 75 publications

(104 reference statements)

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“…The possibility of shaping AgNPs' biological activity by the control of their physicochemical properties is another advantage that induces their wide application [15,16]. It was proven that smaller AgNPs are more toxic than larger ones [17][18][19]. This dependence is correlated to two important factors.…”

Section: Introductionmentioning

confidence: 99%

Antibacterial and Antifungal Properties of Silver Nanoparticles—Effect of a Surface-Stabilizing Agent

et al. 2021

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The biocidal properties of silver nanoparticles (AgNPs) prepared with the use of biologically active compounds seem to be especially significant for biological and medical application. Therefore, the aim of this research was to determine and compare the antibacterial and fungicidal properties of fifteen types of AgNPs. The main hypothesis was that the biological activity of AgNPs characterized by comparable size distributions, shapes, and ion release profiles is dependent on the properties of stabilizing agent molecules adsorbed on their surfaces. Escherichia coli and Staphylococcus aureus were selected as models of two types of bacterial cells. Candida albicans was selected for the research as a representative type of eukaryotic microorganism. The conducted studies reveal that larger AgNPs can be more biocidal than smaller ones. It was found that positively charged arginine-stabilized AgNPs (ARGSBAgNPs) were the most biocidal among all studied nanoparticles. The strongest fungicidal properties were detected for negatively charged EGCGAgNPs obtained using (−)-epigallocatechin gallate (EGCG). It was concluded that, by applying a specific stabilizing agent, one can tune the selectivity of AgNP toxicity towards desired pathogens. It was established that E. coli was more sensitive to AgNP exposure than S. aureus regardless of AgNP size and surface properties.

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Section: Introductionmentioning

confidence: 99%

Antibacterial and Antifungal Properties of Silver Nanoparticles—Effect of a Surface-Stabilizing Agent

et al. 2021

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“…Overall, slightly less soluble metals were observed with R. sativus (e.g., 156 ± 16 µg/L Ni for L. sativa vs. 37 ± 20 µg/L Ni for R. sativus at 5 mg/L NiO NPs), and there were no apparent differences in soluble metal concentrations in the different plant root growth experiments. Previous investigations in our laboratory using algae also revealed low concentrations of dissolved silver and cobalt (0.2–0.5 mg/L, corresponding to 0.1–0.5% of 20–100 mg/L Ag NPs) and Co (0.06–0.44 mg/L, corresponding to <0.02% of Co NPs), suggesting that dissolved metals had a low contribution to the toxicity of NPs in algae [ 51 , 52 ]. The control root length of R. sativus (115–152 mm) was approximately twice that of the L. sativa control (61–74 mm), providing a large surface area for contact with particles or soluble metals.…”

Section: Discussionmentioning

confidence: 80%

Comparisons of the Effect of Different Metal Oxide Nanoparticles on the Root and Shoot Growth under Shaking and Non-Shaking Incubation, Different Plants, and Binary Mixture Conditions

Kong

Koh

2021

Nanomaterials

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We evaluated the toxicity of five metal oxide nanoparticles (NPs) in single or binary mixtures based on root and shoot growth of two plant species under non-shaking and shaking conditions. The effects of NPs on root and shoot growth differed depending on the NP type, incubation condition, and plant type. The half maximal effective concentration (EC50) of NPs based on root growth were significantly lower, by 2.6–9.8 times, under shaking than non-shaking conditions (p = 0.0138). The magnitude of the effects of NPs followed the order CuO > ZnO > NiO >> Al2O3, TiO2. In addition, Lactuca sativa L. was more sensitive to the tested NPs than Raphanus sativus L., with an EC50 0.2–0.7 times lower (p = 0.0267). The observed effects of 12 combinations of binary NP mixtures were slightly, albeit non-significantly, lower than expected, indicative of an additive effect of the individual NPs in the mixtures. The results emphasize the importance of careful plant model selection, appropriate application of incubation conditions, and consideration of chemical mixtures rather than single compounds when evaluating the effects of metal oxide NPs.

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“…Changes at the DNA level are also possible [62]. Depending on the type, shape, size, and concentration of NPs, plant responses to their presence may vary, from stimulation of growth and development, through inhibition, to die-off [63]. The results of studies on agricultural and horticultural plants indicate that these effects also occur under the influence of AgNPs.…”

Section: Discussionmentioning

confidence: 99%

Silver Nanoparticles (AgNPs) in Urea Solution in Laboratory Tests and Field Experiments with Crops and Vegetables

Jaskulski

Jaskulska

Majewska³

et al. 2022

Materials

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Nanotechnology and nanomaterials, including silver nanoparticles (AgNPs), are increasingly important in modern science, economics, and agriculture. Their biological activity involves influencing plant health, physiological processes, growth, and yields, although they can also be toxic in the environment. A new fertiliser was made based on a urea solution with a relatively low content of AgNPs obtained by the reduction of silver nitrate V. Laboratory tests were used to assess the effect of a fertiliser solution containing 10 ppm AgNPs on the germination of agricultural plant seeds (barley, peas, oilseed rape) and vegetables (radish, cucumber, lettuce) and its foliar application on chlorophyll content, stomatal conductance, and seedling biomass. Field experiments were conducted to assess the effect that a foliar application of 15 ppm AgNPs in working liquid had on physiological plant parameters and yields of rape and cucumber. The AgNPs in the tested fertiliser reduced infestation of the germinating seeds by pathogens and positively affected the physiological processes, productivity, and yields of plants. Plant response depended on plant species and habitat conditions. Reduced pathogen infestation of seeds, higher germination energy, increased chlorophyll content and stomatal conductance, and higher seedling masses all occurred under the influence of AgNPs, mainly in oilseed rape and cucumber, and especially under thermal stress. The beneficial effect of AgNPs on the yield of these plants occurred in years of unfavourable weather conditions. The positive agricultural test results, especially under stress conditions, indicate that fertiliser produced with AgNPs as an ingredient may reduce the use of pesticides and highly concentrated mineral fertilisers. Such a fertiliser is fully in line with the idea of sustainable agriculture. However, research on the effects that AgNPs and fertiliser have on the environment and humans should continue.

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Evaluation of the Effects of Particle Sizes of Silver Nanoparticles on Various Biological Systems

Cited by 22 publications

References 75 publications

Antibacterial and Antifungal Properties of Silver Nanoparticles—Effect of a Surface-Stabilizing Agent

Antibacterial and Antifungal Properties of Silver Nanoparticles—Effect of a Surface-Stabilizing Agent

Comparisons of the Effect of Different Metal Oxide Nanoparticles on the Root and Shoot Growth under Shaking and Non-Shaking Incubation, Different Plants, and Binary Mixture Conditions

Silver Nanoparticles (AgNPs) in Urea Solution in Laboratory Tests and Field Experiments with Crops and Vegetables

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