Evaluation of the Effect of Education Provided by Pharmacists on Hyperlipidemic Patient’s Adherence to Medications and Blood Level of Lipids

Abstract

Background: Hyperlipidemia is one of the most common chronic diseases. Studies show that many patients have suboptimal adherence to statin medication which leads to serious negative health consequences. The aim of this study was the evaluation of the effect of education by pharmacists for hyperlipidemic patients treated with statins on patient's adherence to medication and their level of blood lipids. Material & Methods:This clinical trial included 50 patients with heart disease treated with statins who referred to the Hamadan Farshchian Hospital from January to June 2016. The study's data collection tools included a demographic and Morisky questionnaire and their lipid profile before and 6 month after intervention. Data were analyzed by SPSS/16 using T-test, Mann-Withney and X2 tests. Results: Data analysis reflects the homogeneity of medication adherence and the levels of lipid profile in both groups before the intervention but after intervention the medication adherence increased in the intervention group (p < 0.001) and level of LDL significantly decreased (p = 0.02), however, after the intervention there were no statistical difference in the level of HDL, triglyceride and total cholesterol in both groups. Conclusion: Findings of the study suggest that educational counseling by pharmacists could have a positive role in patient's adherence to drugs and blood level of LDL.

Anti-Hyperlipidemic Effect of Zinc complex of Betulinic acid in High Fat Diet- Induced Hyperlipidemia

“…Among lipid-lowering drugs, Statins provide the key support for treating hyperlipidemia by inhibiting the hepatic synthesis of cholesterol and consequently reducing other lipid fractions 5 . Despite the statins demonstrating agreeable results, patient compliance has been reported to be only 40%-60% 6 , the reason being adverse effects such as digestive system disturbances, myalgia, myositis, and rhabdomyolysis 7 , raised levels of glucose, glycosylated hemoglobin (HbA1C ) 8 and elevation of transaminases, thereby limiting the statins usefulness in acute and chronic liver diseases 9 . During the last couple of decades, phytochemicals derived from squalene and terpenoids have received the most attention due to their vast range of biological actions 10 .…”