Evaluation of the Effect of Selected Physiological Fluid Contaminants on the Mechanical Properties of Selected Medium-Viscosity PMMA Bone Cements

Karpiński, Robert; Szabelski, Jakub; Krakowski, Przemysław; Jojczuk, Mariusz; Jonak, Józef; Nogalski, Adam

doi:10.3390/ma15062197

Cited by 17 publications

(10 citation statements)

References 79 publications

(79 reference statements)

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“…Bone cement, or polymethylmethacrylate (PMMA), has been used in surgical fixation of protheses over the last 60 years [ 59 , 60 , 61 , 62 ]. The primary function of bone cement is to transfer forces from the bone to the prosthesis [ 63 , 64 ].…”

Section: Cemented Knee Replacementmentioning

confidence: 99%

Cemented vs. Cementless Fixation in Primary Knee Replacement: A Narrative Review

Wilczyński,

Bieniek,

Krakowski

et al. 2024

Materials

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Knee osteoarthritis (OA) is one of the leading causes of disability around the globe. Osteoarthritis is mainly considered a disease affecting the elderly. However, more and more studies show that sports overuse, obesity, or congenital disorders can initiate a pathologic cascade that leads to OA changes in the younger population. Nevertheless, OA mostly affects the elderly, and with increasing life expectancy, the disease will develop in more and more individuals. To date, the golden standard in the treatment of the end-stage of the disease is total joint replacement (TJR), which restores painless knee motion and function. One of the weakest elements in TJR is its bonding with the bone, which can be achieved by bonding material, such as poly methyl-methacrylate (PMMA), or by cementless fixation supported by bone ingrowth onto the endoprosthesis surface. Each technique has its advantages; however, the most important factor is the revision rate and survivor time. In the past, numerous articles were published regarding TJR revision rate, but no consensus has been established yet. In this review, we focused on a comparison of cemented and cementless total knee replacement surgeries. We introduced PICO rules, including population, intervention, comparison and outcomes of TJR in a PubMed search. We identified 783 articles published between 2010 and 2023, out of which we included 14 in our review. Our review reveals that there is no universally prescribed approach to fixate knee prostheses. The determination of the most suitable method necessitates an individualized decision-making process involving the active participation and informed consent of each patient.

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Section: Cemented Knee Replacementmentioning

confidence: 99%

Cemented vs. Cementless Fixation in Primary Knee Replacement: A Narrative Review

Wilczyński,

Bieniek,

Krakowski

et al. 2024

Materials

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“…The use of bone substitutes is increasingly noticed, and they are used with two main advantages in mind: an ability to integrate with the regenerating bone and a strength similar to the [ 87 , 88 ] cortical bone. The most commonly used are ceramics or hydroxyapatite cement, which the patient’s bone uses up and replaces with bone tissue [ 89 , 90 , 91 ]. Recent studies show that patients with transplanted bone substitutes experience less pain, have fewer complications, and are more agile than patients with other types of transplants [ 92 , 93 ].…”

Section: Bone Graftsmentioning

confidence: 99%

Application of 3D Printing in Bone Grafts

Brachet

Belzek

Furtak

et al. 2023

Cells

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The application of 3D printing in bone grafts is gaining in importance and is becoming more and more popular. The choice of the method has a direct impact on the preparation of the patient for surgery, the probability of rejection of the transplant, and many other complications. The aim of the article is to discuss methods of bone grafting and to compare these methods. This review of literature is based on a selective literature search of the PubMed and Web of Science databases from 2001 to 2022 using the search terms “bone graft”, “bone transplant”, and “3D printing”. In addition, we also reviewed non-medical literature related to materials used for 3D printing. There are several methods of bone grafting, such as a demineralized bone matrix, cancellous allograft, nonvascular cortical allograft, osteoarticular allograft, osteochondral allograft, vascularized allograft, and an autogenic transplant using a bone substitute. Currently, autogenous grafting, which involves removing the patient’s bone from an area of low aesthetic importance, is referred to as the gold standard. 3D printing enables using a variety of materials. 3D technology is being applied to bone tissue engineering much more often. It allows for the treatment of bone defects thanks to the creation of a porous scaffold with adequate mechanical strength and favorable macro- and microstructures. Bone tissue engineering is an innovative approach that can be used to repair multiple bone defects in the process of transplantation. In this process, biomaterials are a very important factor in supporting regenerative cells and the regeneration of tissue. We have years of research ahead of us; however, it is certain that 3D printing is the future of transplant medicine.

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“…Prostheses made with this technique adequately protect the tissues and present a mechanical strength analogous to natural human bone [ 122 ]. In addition, PMMA-based bone cement can be used to stiffen endoprostheses with the patient’s bone [ 204 , 205 ].…”

Section: 3d Cranioplastymentioning

confidence: 99%

Low-Cost Cranioplasty—A Systematic Review of 3D Printing in Medicine

et al. 2022

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The high cost of biofabricated titanium mesh plates can make them out of reach for hospitals in low-income countries. To increase the availability of cranioplasty, the authors of this work investigated the production of polymer-based endoprostheses. Recently, cheap, popular desktop 3D printers have generated sufficient opportunities to provide patients with on-demand and on-site help. This study also examines the technologies of 3D printing, including SLM, SLS, FFF, DLP, and SLA. The authors focused their interest on the materials in fabrication, which include PLA, ABS, PET-G, PEEK, and PMMA. Three-dimensional printed prostheses are modeled using widely available CAD software with the help of patient-specific DICOM files. Even though the topic is insufficiently researched, it can be perceived as a relatively safe procedure with a minimal complication rate. There have also been some initial studies on the costs and legal regulations. Early case studies provide information on dozens of patients living with self-made prostheses and who are experiencing significant improvements in their quality of life. Budget 3D-printed endoprostheses are reliable and are reported to be significantly cheaper than the popular counterparts manufactured from polypropylene polyester.

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Evaluation of the Effect of Selected Physiological Fluid Contaminants on the Mechanical Properties of Selected Medium-Viscosity PMMA Bone Cements

Cited by 17 publications

References 79 publications

Cemented vs. Cementless Fixation in Primary Knee Replacement: A Narrative Review

Cemented vs. Cementless Fixation in Primary Knee Replacement: A Narrative Review

Application of 3D Printing in Bone Grafts

Low-Cost Cranioplasty—A Systematic Review of 3D Printing in Medicine

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