Evaluation of the effect of limited food consumption on radiographic evidence of osteoarthritis in dogs

Kealy, Richard D.; Lawler, Dennis F.; Ballam, J.M.; Lust, George; Biery, Darryl N.; Smith, Gail K.; Mantz, Sandra L.

doi:10.2460/javma.2000.217.1678

Cited by 167 publications

(150 citation statements)

References 9 publications

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“…The mean age of the Cairn Terrier was 4.9 years at the second evaluation. The mean interval of 38 months between evaluations should be enough time to allow development of osteoarthritis in dogs initially scored C, D or E. This is supported by Kealy, et al, Smith, et al, and Farrell, et al who all found progression of osteoarthritis with time and Malm, et al found significant increase of pain in dogs suffering from osteoarthritis after 12 months interval examinations most published studies of progression of osteoarthritis in the dogs are based on larger breeds and no publication concerning small breed dogs [7][8][9][10][11]. However, there are a few publications on the outcome of specific orthopaedic treatment gives better results in small breed dogs first of all due to weight control has an indirectly influence on the degenerative joint disease by reducing stresses on the joint [12][13][14].…”

supporting

confidence: 62%

The Prevalence of Coxofemoral Osteoarthritis in Small Dog Breeds and HD Screening in Cairn Terries A Clinical Radiological Study

Arnbjerg¹

2017

SOJVS

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Background: The prevalence of coxofemoral osteoarthritis being very high, > 40 %, in some large dog breeds. The aim of the study was to estimate the prevalence of osteoarthritic changes in the hip joints in small dog breeds and study the clinical relevance of Hip Dysplasia scoring in Cairn Terries in Denmark. Methods:In a five-year-period study of 2423 small dog breeds (< 15 kg) at the University Hospital, Copenhagen the prevalence of osteoarthritis in the hip joints was calculated A full clinical examination was performed and hip joint radiographs taken in 18 Cairn Terriers, earlier officially scored for hip dysplasia by The Danish Kennel Club, 13 of them with a score of C, D or E respectively. Results:The prevalence of coxofemoral osteoarthritis in small dog breeds was found to be 0.5 %, which is in accordance with earlier published studies in small dog breeds in other countries.In 18 Cairn Terriers, no correlation was found between the initial Hip Dysplasia scoring and clinical signs indicating discomfort. No evidence of osteoarthritis and no progression of hip joint laxity or deformation could be found on the follow up radiographs taken > 18 months (mean. 38 months) after the initial radiological examination evaluated for official HD screening. Conclusion:Due to the very low prevalence in osteoarthritis in small dog breeds and low clinical significance of the radiological scoring of the hips in Cairn Terrier according to parameters set by FCI it cannot be recommended to use the same parameters in Cairn Terrier as in large dog breeds in routine screening programmes for Hip Dysplasia in Cairn Terriers. Keywords Material & MethodsThe prevalence studyFor presence of osteoarthritis changes (malformation of femoral head, acetabulum, sclerosis, periarticular new bone formation) was performed retrospectively on radiographs of purebred small dogs (> 1 year of age, body weight < 15 kg) taken at the Small Animal Hospital at University of Copenhagen in a period of 5 years (2006 -2010). During this period, a total of 2423 small pure breed dogs were presented for all kind of consultation. From these 229 Ventro-Dorsal radiographs of the pelvic area from 37 different pure breeds were included in the study (Table 1). Table 1 shows the material of dogs on which the prevalence's are calculated and organized in relations to different breeds and the prevalences in the different breeds showing the average prevalence to be 0.5 %. The Shetland Sheepdogs and the French bulldog hawing the highest individual prevalence, 3.9 and 1.9 respectively. Dachshound, Miniature Schnauzer, Papillon and Yorkshire Terrier having 0.0 % in this material.To be able to evaluate if there is an age or gender related prevalence of osteoarthritic changes, the dogs were separated in 4 groups (12 -35 months and > 36 months and gender groups).The age and clinical findings were recorded. Dogs were excluded if affected by Legg-Calve-Perthes disease, femoral head excision or a fracture or luxation of the pelvic bones. If the same dog was examined more ...

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supporting

confidence: 62%

The Prevalence of Coxofemoral Osteoarthritis in Small Dog Breeds and HD Screening in Cairn Terries A Clinical Radiological Study

Arnbjerg¹

2017

SOJVS

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“…Son animales de similar envergadura, no habiendo ningún obeso, puesto que son animales de trabajo que realizan ejercicio y tienen una dieta sana y equilibrada. Además, la dieta puede ser el motivo por el que, en caso de que el animal desarrolle en un futuro la CHD, su presentación sea tardía y más leve, tal y como se describe en la bibliografía [41][42][43][44][45] . En cuanto a la predisposición racial, en nuestro estudio no se observan diferencias estadísticamente significativas, algo que…”

Section: Discussionunclassified

El Pennhip modificado y la sinfisiodesis juvenil pubiana como prevención de displasia de cadera canina en las Fuerzas Armadas

et al. 2015

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“…Previous studies have demonstrated that dogs with CR have reduced shoulder OA, 6-year postdiet intervention, and also show decreased incidence of a combination of shoulder and hip OA (Kealy et al 2000;Runge et al 2008). Additionally, the implementation of CR has been linked to greater joint mobility as well as lower triglycerides in a canine OA model (Kealy et al 2000;Lawler et al 2008). A more detailed analysis of the effects of CR on arthritic bone and cartilage changes, and joint inflammation could provide further insight into the mechanisms by which diet and body weight influence OA development with age.…”

Section: Introductionmentioning

confidence: 98%

“…The reduction of adipose tissue, and thereby its associated inflammation, may decrease the possibility of developing a metabolic syndrome, which is typically characterized by insulin insensitivity, dyslipidemia, and hypertension (Weiss and Fontana 2011). Previous studies have demonstrated that dogs with CR have reduced shoulder OA, 6-year postdiet intervention, and also show decreased incidence of a combination of shoulder and hip OA (Kealy et al 2000;Runge et al 2008). Additionally, the implementation of CR has been linked to greater joint mobility as well as lower triglycerides in a canine OA model (Kealy et al 2000;Lawler et al 2008).…”

Section: Introductionmentioning

confidence: 99%

Life-long caloric restriction does not alter the severity of age-related osteoarthritis

McNeill

Rabey

et al. 2014

AGE

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Chronic adipose tissue inflammation and its associated adipokines have been linked to the development of osteoarthritis (OA). It has been shown that caloric restriction may decrease body mass index and adiposity. The objectives of this study were to investigate the effect of lifelong caloric restriction on bone morphology, joint inflammation, and spontaneously occurring OA development in aged mice. C57BL/NIA mice were fed either a calorie-restricted (CR) or ad libitum (AL) diet starting at 14 weeks of age. All mice were sacrificed at 24 months of age. Adipose tissue and knee joints were then harvested. Bone parameters of the joints were analyzed by micro-CT. OA and joint synovitis were determined using histology and semiquantitative analysis. Lifelong caloric restriction did not alter the severity of OA development in C57BL/NIA aged mice, and there was no difference in the total joint Mankin score between CR and AL groups (p=0.99).Mice also exhibited similar levels of synovitis (p=0.54). The bone mineral density of the femur and the tibia was comparable between the groups with a small increase in cancellous bone volume fraction in the lateral femoral condyle of the CR group compared with the AL group. Lifelong caloric restriction did not alter the incidence of OA or joint synovitis in C57BL/NIA mice, indicating that a reduction of caloric intake alone was not sufficient to prevent spontaneous age-related OA. Nonetheless, early initiation of CR continued throughout a life span did not negatively impact bone structural properties.

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Evaluation of the effect of limited food consumption on radiographic evidence of osteoarthritis in dogs

Abstract: Prevalence and severity of osteoarthritis in several joints was less in dogs with long-term reduced food intake, compared with control dogs. Food intake is an environmental factor that may have a profound effect on development of osteoarthritis in dogs.

Cited by 167 publications

References 9 publications

The Prevalence of Coxofemoral Osteoarthritis in Small Dog Breeds and HD Screening in Cairn Terries A Clinical Radiological Study

The Prevalence of Coxofemoral Osteoarthritis in Small Dog Breeds and HD Screening in Cairn Terries A Clinical Radiological Study

El Pennhip modificado y la sinfisiodesis juvenil pubiana como prevención de displasia de cadera canina en las Fuerzas Armadas

Life-long caloric restriction does not alter the severity of age-related osteoarthritis

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