Evaluation of the effect of intrathecal clonidine to decrease shoulder tip pain in laparoscopy under spinal anaesthesia

Ghodki, Poonam S; Sardesai, Shalini; Thombre, Shalini

doi:10.4103/0019-5049.65370

Cited by 22 publications

(26 citation statements)

References 20 publications

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“…Total consumption of analgesics in first post-operative 24 hours was also low. Ghodki et al 14 added 30μg clonidine to intrathecal bupivacaine for laparoscopic surgeries and evaluated for shoulder tip pain. They found that incidence of shoulder tip pain was less and post operative analgesia was prolonged significantly.…”

Section: Discussionmentioning

confidence: 99%

To Study the Efficacy of 45

2017

IJSR

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Section: Discussionmentioning

confidence: 99%

To Study the Efficacy of 45

2017

IJSR

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“…7,13 Pada penelitian ini kami mencatat pula efek samping pascaanestesia, seperti kejadian sedasi pada kelompok I sebesar 48% dan pada kelompok II 55%. Kejadian mual muntah tidak ditemukan pada kedua kelompok.…”

Section: Terdapat Tiga Prinsip Yang Menjadi Alasanunclassified

Comparison of 15 µg and 30 µg Intrathecal Clonidine in 12.5 mg 0.5% Bupivacain for Post Spinal Anesthesia Shivering in Caesarean Section

Mansur¹,

Pradian²,

Bisri³

2015

jap

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AbstrakMenggigil pascaanestesi spinal merupakan efek samping yang sering terjadi. Penelitian ini bertujuan untuk membandingkan penambahan klonidin intratekal antara 15 µg dan 30 µg pada 12,5 mg bupivakain. Penelitian adalah eksperimental dengan uji klinis rancangan acak lengkap terkontrol buta tunggal pada 80 wanita yang menjalani seksio sesarea dengan anestesi spinal, status fisik American Society of Anesthesiologist (ASA) II, berusia 18-42 tahun, dibagi secara random menjadi dua kelompok, kelompok I menggunakan 12,5 mg bupivakain 0,5 % dan klonidin 15 µg, sedangkan kelompok II mendapat penambahan klonidin 30 µg. Penelitian dilakukan di Rumah Sakit Dr. Hasan Sadikin Bandung pada periode Oktober-Desember 2011. Perbandingan proporsi kejadian kedua kelompok dianalisis secara statistik menggunakan uji chi-kuadrat, sedangkan derajat menggigil dengan Uji Mann-Whitney. Hasil penelitian menunjukkan bahwa kejadian menggigil pascaanestesi pada kelompok II sebanyak 2 pasien, sedangkan pada kelompok I adalah 10 pasien. Simpulan, penambahan klonidin intaratekal 30 µg pada bupivacain 0,5% untuk mencegah menggigil pascaanestesi spinal lebih baik dibandingkan dengan klonidin intratekal 15 µg. Shivering is a frequently experienced side effect of post-subarachnoid block. This study aimed to determine the which of 15 µg dose and 30 µg dose of intrathecal Clonidine is better prevents Post anaesthesia shivering. The research was conducting by clinical trials of a single blind randomized controlled design. Eighty pregnant female patients with ASA physical status II, aged 18-42 years, who underwent a caesarean section were randomly divided into two groups, spinal anesthesia performed by using 12.5 0.5% mg bupivacain and 15 µg clonidine in Group I and the same dose of bupicavain but with 30 µg clonidine in group II. The incidence proportion of both groups were statistically compared using chi square test, while the degree of shivering was analyzed using Mann-Whitney test. The results showed that the characteristics of patient data and the core temperature did not statistically different between the two groups. The incidence and degree of shivering were different between the two groups, with were 2 patients experienced shivering incidence in group II and 10 patients experienced the incidence in group I. It is concluded that the addition of intrathecal 30 µg clonidine to 0.5% bupivacain prevents post-subarachnoid spinal block shivering better than in trathecal clonidine 15 µg.

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“…[5][6][7] Sedation and analgesia in the form of midazolam, opioids and other agents like ketamine and propofol have been used. 8,9 In present experience we have found that the amount of sedation and analgesia needed for delineating the discomfort and shoulder pain in gynecological laparoscopic procedures leads to respiratory depression and hypoventilation.…”

Section: Introductionmentioning

confidence: 99%