Evaluation of the effect of injectable platelet-rich fibrin (I-PRF) in reducing the resorption of fat graft during facial lipostructure: A randomized clinical trial

Alkerdi, Kamal; Alsabek, Laith; Alkhouli, Muaaz; Al‐Nerabieah, Zuhair; Jaafo, Hassan

doi:10.17219/dmp/136974

Cited by 4 publications

(6 citation statements)

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“…According to several peer-reviewed scientific papers [ 31 – 33 ], the uses of PRP and PRF in dentistry are many, especially in the field of endodontics, periodontal treatments, oral surgery, and others, because of their role in the regeneration process and regenerative medicine.…”

Section: Introductionmentioning

confidence: 99%

“…A randomized controlled clinical study [ 31 ] conducted at Damascus University by Al-Kurdi et al demonstrated the efficacy of I-PRF in reducing the resorption of fat following facial lipostructure. In several animal laboratory studies, experiments showed that platelet-rich plasma facilitates the repair of cartilaginous and osteochondral lesions [ 34 , 35 ].…”

Section: Introductionmentioning

confidence: 99%

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Evaluation of the efficacy of platelet rich fibrin (I-PRF) intra-articular injections in the management of internal derangements of temporomandibular joints – a controlled preliminary prospective clinical study

Manafikhi

Ataya

Heshmeh

2022

BMC Musculoskelet Disord

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Background The temporomandibular joint (TMJ) is one of the most complex joints in the body. Temporomandibular disorders (TMD) are among the most troublesome disorders for patients, as they can cause pain, affect oral functions and disturb dentists on the level of diagnosis and treatment. The most common symptoms of temporomandibular joint disorders are articulated sounds (such as clicking or TMJ crepitation), joint pain in comfort and function situations (jaw movements), pain or strain in masseter and jaw muscles and or restricted mandibular movements. One of the most modern biocompatible substances used to treat joint disorders, including the TMJ, is platelet-rich plasma (PRP) and injectable platelet-rich fibrin (I-PRF). This study aims to evaluate the efficacy of platelet-rich fibrin (I-PRF) intra-articular injections in managing internal derangements of temporomandibular. Methods Twenty patients suffering from a unilateral click due to temporomandibular disorders were individually injected with 1 mL of (I-PRF) twice 1 week apart into the superior joint space of the TMJ with the internal disorder. Data were recorded and evaluated by the Helkimo index. This evaluation was conducted three times; 1 week after the first injection, 1 week after the second injection, and 6 months after the first injection. Results The clicking disappeared entirely in 14 out of 20 patients after 1 week of getting the first injection, and in all patients after 1 week of getting the second injection, and returned to two of them after a six-month since the first injection. Conclusion Preliminary results showed the efficacy of the Injectable Platelet-Rich Fibrin (I-PRF) in managing articular clicking in patients with internal disorders of the temporomandibular joint. Injectable Platelet Rich Fibrin has significant clinical efficacy in treating the articular clicking resulting from internal temporomandibular joint disorders.

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Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Evaluation of the efficacy of platelet rich fibrin (I-PRF) intra-articular injections in the management of internal derangements of temporomandibular joints – a controlled preliminary prospective clinical study

Manafikhi

Ataya

Heshmeh

2022

BMC Musculoskelet Disord

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“…Clinical studies start confirming these results: Gentile et al ( 52 ) showed 69% graft retention when combining fat with PRP, which was significantly higher than fat grafting alone (39%) in their series of 50 patients. Several studies have been conducted on face treatment using fat transfer, showing similarly positive results ( 53 - 55 ). Finally, using endothelial cells has shown excellent results in preclinical models for enhancing fat grafting survivability ( 56 ).…”

Section: Literature Review Of Tissue- and Bio-engineering Approaches ...mentioning

confidence: 91%

Tissue engineering strategies for breast reconstruction: a literature review of current advances and future directions

Berkane,

Oubari,

van Dieren

et al. 2024

Ann Transl Med

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Background and Objective Mastectomy is a primary treatment for breast cancer patients, and both autologous and implant-based reconstructive techniques have shown excellent results. In recent years, advancements in bioengineering have led to a proliferation of innovative approaches to breast reconstruction. This article comprehensively explores the promising perspectives offered by bioengineering and tissue engineering in the field of breast reconstruction. Methods A literature review was conducted between April and June 2023 on PubMed and Google Scholar Databases. All English and French articles related to bioengineering applied to the field of breast reconstruction were included. We used the Evidence-Based Veterinary Medicine Association (EBVM) Toolkit 14 checklist for narrative reviews as a quality assurance measure and the Scale for the Assessment of Narrative Review Articles (SANRA) tool to self-assess our methodology. Key Content and Findings Over 130 references related to breast bioengineering were included. The analysis revealed four key applications: enhancing the quality of the skin envelope, improving the viability of fat grafting, creating breast shape and volume via bio-printing, and optimizing nipple reconstruction through engineering techniques. The primary identified approaches revolved around establishing structural support and enhancing cellular viability. Structural techniques predominantly involved the implementation of 3D printed, decellularized, or biocompatible material scaffolds. Meanwhile, promoting cellular content trophicity primarily focused on harnessing the regenerative potential of adipose-derived stem cells (ADSCs) and increasing the tissue’s survivability and cell trophicity. Conclusions Tissue and bioengineering hold immense promise in the field of breast reconstruction, offering a diverse array of approaches. By combining existing techniques with novel advancements, they have the potential to significantly enhance the therapeutic options available to plastic and reconstructive surgeons.

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“…90 Regarding other uses of PRF in facial esthetics, several studies have noted that i-PRF is able to improve fat grafting and its stability. [91][92][93] In a prospective single-center study, Hassan i-PRF for the treatment of alopecia. 97 Notably, further improvements have also been reported when i-PRF is utilized to stimulate hair regeneration when compared to PRP (Figure 19, Figure S1: QR Code 15 ).…”

Section: Clini C Al Us E Of I-prf In Facial E S the Ti C S And Hair R...mentioning

confidence: 99%

“…Regarding other uses of PRF in facial esthetics, several studies have noted that i‐PRF is able to improve fat grafting and its stability 91–93 . In a prospective single‐center study, Hassan and colleagues found that i‐PRF significantly improved skin surface spots ( p = 0.01) and pores ( p = 0.03) at the 3‐month follow‐up.…”

Section: Clinical Use Of I‐prf In Facial Esthetics and Hair Regrowthmentioning

confidence: 99%

Ten years of injectable platelet‐rich fibrin

Miron,

Gruber,

Farshidfar

et al. 2023

Periodontology 2000

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The use of platelet‐rich fibrin (PRF) has seen widespread advantages over platelet‐rich plasma (PRP) in many fields of medicine. However, until 2014, PRF remained clinically available only in its solid clotted form. Modifications to centrifugation protocols and tube technology have led to the development of a liquid injectable version of PRF (i‐PRF). This narrative review takes a look back at the technological developments made throughout the past decade and further elaborates on their future clinical applications. Topics covered include improvements in isolation techniques and protocols, ways to further concentrate i‐PRF, and the clinical impact and relevance of cooling i‐PRF. Next, various uses of i‐PRF are discussed, including its use in regenerative periodontology, implantology, endodontics, temporomandibular joint injections, and orthodontic tooth movement. Furthermore, various indications in medicine are also covered, including its use in sports injuries and osteoarthritis of various joints, treatment of diabetic ulcers/wound care, and facial esthetics and hair regrowth. Finally, future applications are discussed, mainly its use as a drug delivery vehicle for small biomolecules, such as growth factors, antibiotics, exosomes, and other medications that may benefit from the controlled and gradual release of biomolecules over time.

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Evaluation of the effect of injectable platelet-rich fibrin (I-PRF) in reducing the resorption of fat graft during facial lipostructure: A randomized clinical trial

Cited by 4 publications

References 0 publications

Evaluation of the efficacy of platelet rich fibrin (I-PRF) intra-articular injections in the management of internal derangements of temporomandibular joints – a controlled preliminary prospective clinical study

Evaluation of the efficacy of platelet rich fibrin (I-PRF) intra-articular injections in the management of internal derangements of temporomandibular joints – a controlled preliminary prospective clinical study

Tissue engineering strategies for breast reconstruction: a literature review of current advances and future directions

Ten years of injectable platelet‐rich fibrin

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