Evaluation of The Economic Impact of Ferric Carboxymaltose Use For The French National Health Insurance And The French Hospitals Organization

Abstract

chart review study of patients aged 1-12 years with a primary varicella diagnosis between 2011 and 2015. Healthcare resource utilization (HCRU) associated with varicella, unit costs, and work loss were used to estimate direct and indirect costs. All costs are presented in 2015 Polish Zloty (PLN) / Euros (€ ). Results: 150 children with varicella were included (75 outpatients, 75 inpatients), with a mean age of 3.9 (SD: 2.6) and 4.2 (SD: 2.3) years, respectively. One or more complications were experienced by 14.7% of outpatients and 82.7% of inpatients, the most common being skin and soft tissue infections, dehydration, pneumonia, and cerebellitis. HCRU estimates included use of over-the-counter (OTC) medications (80.0% outpatients, 81.3% inpatients), prescription medications (80.0% outpatients, 93.3% inpatients), tests/procedures (0.0% outpatients, 69.3% inpatients), and consultation with allied health professionals (0.0% outpatients, 24.0% inpatients). The average duration of hospital stay was 4.7 (95% CI: 4.1 , 5.3) days for inpatients. The total combined direct and indirect cost per varicella case was 5013.3 PLN / € 1,198.1, for inpatients and 1027.2 PLN/ € 245.5, for outpatients. The overall annual cost of varicella in Poland for children aged 1-15 years in 2015 was estimated at 177,655,759.6 PLN,/€ 42,458,716.0. ConClusions: Varicella is associated with substantial clinical burden in Poland, resulting in the utilization of a significant amount of healthcare resources.