Evaluation of the Corrosive Therapy of Injection of Silver Nitrate Solution into Perianal Fistulas in Infants

Abstract

This study included 113 infants with perianal fistulas. In these infants, time of onset of perianal abscesses after birth, the number of anal fistulas, the number of repetitions of treatment and the time interval between treatment and healing were evaluated. Eighty-three had 1 fistula, 23 had 2 fistulas and 7 had 3 or more fistulas. Half of the multi-tract anal fistulas occurred simultaneously and the other half occurred at different times. Peaks in the incidence of these fistulas were observed at 1 month and 6 months after birth (122 112 days). An edgeless U-shaped needle was used to inject 30 silver nitrate solution into the internal orifice of perianal fistulas. Subsequent neutralization was performed by injecting saline into the same internal orifice. In patients with multiple fistulas, each was treated separately in the same manner simultaneously.

Local irrigation with silver nitrate, a non-surgical approach for persistent anal fistula

“…6 In the same line, Utsunomiya et al have reported a cohort of 113 infants diagnosed of perineal fistula treated with SN 30% solution, with an impressive complete healing rate of 73% without major complications. 7 To conclude, we provide additional evidence for the use of SN 1% solution irrigation in recurrent o persistent anal fistula. We report a complete healing rate of 44.4% performing a non-invasive procedure, with a favourable safety profile, and feasible to perform in outpatient clinic.…”

Histoacryle Injection VS. Silver Nitrate Injection in Treatment of Low Non Branching Anal Fistula

“…In the same line, (22) have reported a cohort of 113 infants diagnosed of anal fistula treated with SN 30% solution, with an impressive complete healing rate of 73% without major complications.…”