Evaluation of the chronic obstructive pulmonary disease assessment test in <scp>J</scp>apanese outpatients

Horita, Nobuyuki; Yomota, Makiko; Sasaki, Masahiro; Morita, Satoshi; Shinkai, Masaharu; Ishigatsubo, Yoshiaki; Kaneko, Takeshi

doi:10.1111/crj.12062

Cited by 7 publications

(7 citation statements)

References 26 publications

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“…This was in line with a population-based survey in Japan that revealed a mean CAT score of 16 points – similar to that observed in this study 35. Earlier studies have shown a strong correlation with the CAT questionnaire with severity of airflow obstruction, dyspnea and comorbidities in Japanese patients 13,36. Overall, these data show that COPD symptomatology remains an important factor on impairment of HRQoL.…”

Section: Discussionsupporting

confidence: 92%

COPD uncovered: a cross-sectional study to assess the socioeconomic burden of COPD in Japan

Igarashi¹,

Fukuchi²,

Hirata³

et al. 2018

COPD

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BackgroundCOPD remains a major health problem in Japan. Patients with COPD experience a reduced quality of life (QoL) and have a higher chance of work impairment and productivity loss. However, there is a lack of data on the impact of COPD in terms of QoL and work activity impairment in Japan. This study assessed the socioeconomic burden of COPD in Japan and the impact it may have on the working age population.Patients and methodsThis was a 2-year retrospective chart review in COPD patients aged ≥40 years, with at least one health care visit to clinic or hospital in the previous 12 months. Patients were required to have available medical charts for at least the previous 24 months. Symptoms were assessed using COPD assessment test score; EuroQoL Group 5 Dimension (EQ-5D-5L) and work productivity and activity impairment general health questionnaires were used to evaluate health-related QoL and work productivity, and health care resource utilization data were obtained from clinical charts.ResultsIn total, 71 patients aged <65 years, and 151 patients aged ≥65 years were included; the majority of patients had moderate or severe airflow limitation. Exacerbations (moderate or severe) were reported by ~35% of patients in both age groups; 52.1% and 62.9% of patients in the <65-year and ≥65-year age groups had COPD assessment test scores ≥10. EQ-5D-5L index scores in the <65-year and ≥65-year age groups were 0.79 and 0.77, respectively. Work productivity and activity impairment scores were higher in <65-year age group. Annual costs of health care resource use per patient in the <65-year and ≥65-year age groups were ¥438,975 (US$4,389) and ¥467,871 (US$4,678), respectively. Costs due to productivity loss were estimated to be ¥5,287,024 (US$52,870) in the <65-year age group and ¥3,018,974 (US$30,187) in the ≥65-year age group.ConclusionCOPD represents a significant socioeconomic burden in Japan. Patients with COPD report significant use of health care resources. Higher impact on work impairment and productivity loss was observed frequently in the working age population.

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Section: Discussionsupporting

confidence: 92%

COPD uncovered: a cross-sectional study to assess the socioeconomic burden of COPD in Japan

Igarashi¹,

Fukuchi²,

Hirata³

et al. 2018

COPD

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“… 19 In Japan, 85 patients with COPD from a hospital outpatient clinic showed strong correlations of CAT with airflow obstruction, dyspnea, exercise tolerance, prognostic index, and oxygenation. 20 A recent systematic review evaluated the psychometric properties of the CAT questionnaire and observed a relationship between the CAT and several clinical outcomes, but not for parameters such as sex, age, smoking status, and comorbidities. 21 The most relevant study evaluated 882 consultations from 165 PC physicians in the United Kingdom but was carried out with standardized patients with COPD, played by trained actors.…”

Section: Discussionmentioning

confidence: 99%

Evaluation of the COPD Assessment Test and GOLD patient types: a cross-sectional analysis

Lόpez-Campos¹,

Villar²,

Calero-Acuña³

et al. 2015

COPD

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BackgroundThe COPD Assessment Test (CAT) has been recently developed to quantify COPD impact in routine practice. However, no relationship with other measures in the Global Initiative for Obstructive Lung Disease (GOLD) strategy has been evaluated. The present study aimed to evaluate the relationship of the CAT with other GOLD multidimensional axes, patient types, and the number of comorbidities.MethodsThis was a cross-sectional analysis of the Clinical presentation, diagnosis, and course of chronic obstructive pulmonary disease (On-Sint) study. The CAT score was administered to all participants at the inclusion visit. A GOLD 2011 strategy consisting of modified Medical Research Council scale (MRC) scores was devised to study the relationship between the CAT, and GOLD 2011 axes and patient types. The relationship with comorbidities was assessed using the Charlson comorbidity index, grouped as zero, one to two, and three or more.ResultsThe CAT questionnaire was completed by 1,212 patients with COPD. The CAT maintained a relationship with all the three axes, with a ceiling effect for dyspnea and no distinction between mild and moderate functional impairment. The CAT score increased across GOLD 2011 patient types A–D, with similar scores for types B and C. Within each GOLD 2011 patient type, there was a considerably wide distribution of CAT values.ConclusionOur study indicates a correlation between CAT and the GOLD 2011 classification axes as well as the number of comorbidities. The CAT score can help clinicians, as a complementary tool to evaluate patients with COPD within the different GOLD patient types.

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“…The internal consistency of the CAT was reported in eight studies, with the Cronbach's a range from 0.85-0.98 indicating a high correlation between items [5,9,10,14,15,18,19,21] (table 2). Test-retest was evaluated in five studies to measure reproducibility [5,9,10,14,30] (table 2), with the CAT administered on two different occasions (at baseline and then either 1 or 2 weeks later) for three studies [5,10,30] and on three separate occasions (at baseline, 2 weeks and then 6 weeks later) for one study [14].…”

Section: Reliabilitymentioning

confidence: 99%

The COPD assessment test: a systematic review

et al. 2014

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The COPD assessment test (CAT) is a self-administered questionnaire that measures healthrelated quality of life. We aimed to systematically evaluate the literature for reliability, validity, responsiveness and minimum clinically important difference (MCID) of the CAT.Multiple databases were searched for studies analysing the psychometric properties of the CAT in adults with chronic obstructive pulmonary disease. Two reviewers independently screened, selected and extracted data, and assessed methodological quality of relevant studies using the COSMIN checklist.From 792 records identified, 36 studies were included. The number of participants ranged from 45 to 6469, mean age from 56 to 73 years, and mean forced expiratory volume in 1 s from 39% to 98% predicted. Internal consistency (reliability) was 0.85-0.98, and test-retest reliability was 0.80-0.96. Convergent and longitudinal validity using Pearson's correlation coefficient were: SGRQ-C 0.69-0.82 and 0.63, CCQ 0.68-0.78 and 0.60, and mMRC 0.29-0.61 and 0.20, respectively. Scores differed with GOLD stages, exacerbation and mMRC grades. Mean scores decreased with pulmonary rehabilitation (2.2-3 units) and increased at exacerbation onset (4.7 units). Only one study with adequate methodology reported an MCID of 2 units and 3.3-3.8 units using the anchor-based approach and distribution-based approach, respectively. Most studies had fair methodological quality.We conclude that the studies support the reliability and validity of the CAT and that the tool is responsive to interventions, although the MCID remains debatable. @ERSpublications Studies support the reliability, validity and responsiveness of the CAT as a HRQoL tool but its MCID remains unclear

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Evaluation of the chronic obstructive pulmonary disease assessment test in Japanese outpatients

Abstract: The CAT score, which is obtainable by a simple questionnaire originally designed for QOL assessment, had strong correlations with airflow obstruction, dyspnea, exercise tolerance, prognostic index and oxygenation in Japanese outpatients.

Cited by 7 publications

References 26 publications

COPD uncovered: a cross-sectional study to assess the socioeconomic burden of COPD in Japan

COPD uncovered: a cross-sectional study to assess the socioeconomic burden of COPD in Japan

Evaluation of the COPD Assessment Test and GOLD patient types: a cross-sectional analysis

The COPD assessment test: a systematic review

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