Abstract:Objectives: Evaluate the cellular, humoral immune response and the protection against oral challenge in mice, induced by 255 Gy T. gondii irradiated tachyzoites in a source of 60 Co γ-rays.
Material and Methods:T. gondii tachyzoites were irradiated with 255 Gy, maintained in nitrogen and freezer. C57Bl/6j mice were immunized with irradiated tachyzoites (3 doses). The humoral and cellular response in immunized mice was analyzed. The immunized mice with 255 Gy irradiated tachyzoites (3 doses) were challenged, by… Show more
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