“…Questions arise, however, regarding the ability of these drugs to produce arrhythmias and over the value of prophylactic digitalization. 147 Thus, it has been said on the basis of clinical experience that the combination of digitalization and general anesthesia often produces a more irritable myocardium. 17 Animal experimentation indicates that the over digitalized heart may be more sensitive to epinephrine-induced arrhythmias,163 but cyclopropane tends to improve leO , 163 and ether to abolish 120 digitalis-induced arrhythmias.…”