Evaluation of the Biocidal Capacity of Hypercrosslinked Resins Containing Dithiocarbamate Groups

Abstract

Summary: In this study we report both the development of dithiocarbamate resins from the commercial hypercrosslinked resin MN-250 and the evaluation of the biocidal capacity of this material against E. coli ATCC25922 suspensions. The preparation of dithiocarbamate resins followed a synthetic pathway based on nitration of resins, reduction of nitro groups and reaction with CS 2 in an alkaline medium. The biocidal capacity was evaluated by means of elution of E. coli suspensions (10 3 -10 7 cells/mL) through columns containing the resin and plating on LB nutrient medium solidified with Bacto agar. We can conclude that hypercrosslinked resins with dithiocarbamate groups have potential biocidal action.

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“…At the end of this period, the copolymer was washed with distilled water, ethanol and acetone and dried in an oven at 60°C for 24 hours. (COSTA et al, 2012).…”

Resinas poliméricas reticuladas com ação biocida: atual estado da arte

“…Tanto o produto da primeira etapa (fosforilação) quanto da segunda etapa (formação do grupamento sulfofosforila) apresentaram ação biocida em torno de 100% até a concentração de 10 5 , a partir dessa concentração o material sulfofosforilado apresentou uma eficiência em torno de 80% enquanto o fosforilado caiu para 20% [79] . Costa e colaboradores [80] avaliaram a capacidade biocida de uma resina polimérica hiperreticulada contendo grupos ditiocarbamato. A resina hiperreticulada utilizada neste trabalho foi a resina comercial MN-250 produzida pela Purolite SRL.…”

“…A resina comercial e os produtos das reações de nitração e redução não apresentaram ação biocida para nenhuma das concentrações de E. Coli avaliadas. Já a resina contendo grupos ditiocarbamato mostrou ação biocida significativa para todas as concentrações de E. Coli estudadas, sendo que para a concentração de 10 3 células/mL a ação biocida foi de 92% [80] .…”

Evaluation of antimicrobial action of silver composite microspheres based on styrene-divinylbenzene copolymer

“…Crosslinked copolymer microspheres such as copolymers based on divinylbenzene have been extensively used as supports for chemical catalysts and biocatalysts [8,9] , ion imprinting polymers [10] , and introduction of magnetic particles [11][12][13][14] , adsorbents and absorbents [15,16] and antimicrobial groups [3,5,[17][18][19][20][21][22][23][24][25][26] .…”

“…The introduction of antimicrobial groups in crosslinked copolymers is commonly achieved by chemical modification or impregnation of the antibacterial agent in the polymeric matrix [3] . The polymeric supports employed most often are crosslinked beads made of divinylbenzene (DVB), and the biocidal groups studied are mainly ammonium and phosphonium quaternary groups [3,17,19,22] , charge transfer complexes involving iodine and quaternary ammonium groups [3,17,23] , N-halamines [3,6] , sulfo-derivatives [3,5,18] and metal particles [1][2][3]20,21,[24][25][26] .…”