Evaluation of the antimicrobial and antioxidant activity of 7-hydroxy-4’, 6-dimethoxy-isoflavone and essential oil from Myroxylon peruiferum L.f

Pereira, Rafael; Pereira, Anna Luísa; Ferreira, Marcílio Matos; Fontenelle, Raquel Oliveira dos Santos; Saker-Sampaio, Silvana; Santos, Hélcio Silva dos; Bandeira, Paulo Nogueira; Vasconcelos, Mayron Alves de; Queiroz, José Ájax Nogueira; Braz-Filho, Raimundo; Teixeira, Edson Holanda

doi:10.1590/0001-3765201920180204

Cited by 8 publications

(6 citation statements)

References 44 publications

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“…The increase of antibiotically resistance phenomenon in human and animal pathologies has determined the intensification of research on new natural antimicrobial substances [19,46,47], and in this view, several studies were carried out to investigate the biological activities of Pinaceae EOs and the roles of their molecules. P. abies EO extracted by supercritical carbon dioxide was investigated for antimicrobial properties on E. coli using the isothermal calorimetry technique, and it inhibited the growth and interfered with the metabolic activity of the microorganism [48].…”

Section: Discussionmentioning

confidence: 99%

Liquid and Vapor Phase of Four Conifer-Derived Essential Oils: Comparison of Chemical Compositions and Antimicrobial and Antioxidant Properties

et al. 2021

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In this study, the chemical composition of the vapor and liquid phase of Pinus cembra L., Pinus mugo Turra, Picea abies L., and Abies Alba M. needles essential oils (EOs) was investigated by Headspace-Gas Chromatography/Mass Spectrometry (HS-GC/MS). In the examined EOs, a total of twenty-eight components were identified, most of which belong to the monoterpenes family. α-Pinene (16.6–44.0%), β-pinene (7.5–44.7%), limonene (9.5–32.5%), and γ-terpinene (0.3–19.7%) were the most abundant components of the liquid phase. Such major compounds were also detected in the vapor phase of all EOs, and α-pinene reached higher relative percentages than in the liquid phase. Then, both the liquid and vapor phases were evaluated in terms of antibacterial activity against three Gram-negative bacteria (Escherichia coli, Pseudomonas fluorescens, and Acinetobacter bohemicus) and two Gram-positive bacteria (Kocuria marina and Bacillus cereus) using a microwell dilution assay, disc diffusion assay, and vapor phase test. The lowest Minimum Inhibitory Concentration (MIC) (13.28 mg/mL) and Minimal Bactericidal Concentration (MBC) (26.56 mg/mL) values, which correspond to the highest antibacterial activities, were reported for P. abies EO against A. bohemicus and for A. alba EO against A. bohemicus and B. cereus. The vapor phase of all the tested EOs was more active than liquid phase, showing the inhibition halos from 41.00 ± 10.15 mm to 80.00 ± 0.00 mm for three bacterial strains (A. bohemicus, K. marina, and B. cereus). Furthermore, antioxidant activities were also investigated by 2,2-diphenyl-1-picrylhydrazyl (DPPH) and 2,2′-azinobis (3- ethylbenzothiazoline-6-sulfonic acid) diammonium salt (ABTS) assays, and a concentration-dependent antioxidant capacity for all EOs was found. P. mugo EO showed the best antioxidant activity than the other Pinaceae EOs. The four Pinaceae EOs could be further investigated for their promising antibacterial and antioxidant properties, and, in particular, α-pinene seems to have interesting possibilities for use as a novel natural antibacterial agent.

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Section: Discussionmentioning

confidence: 99%

Liquid and Vapor Phase of Four Conifer-Derived Essential Oils: Comparison of Chemical Compositions and Antimicrobial and Antioxidant Properties

et al. 2021

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“…A 96-well microtiter plate and microbroth dilution method was used to determine the minimum inhibitory concentration (MIC), as previously described [18]. Each well containing 1 × 10 5 to 1 × 10 6 CFU/mL bacteria in MH broth medium (200 μL) was incubated at 37 °C for 24 h with 10 μL of test solutions, which were diluted serially at a 1:5 ratio (concentrations from 10 mg/mL to 1.25 μg/mL).…”

Section: Methodsmentioning

confidence: 99%

Characterization of the anti-Staphylococcus aureus fraction from Penthorum chinense Pursh stems

Ding

Zhang

et al. 2019

BMC Complement Altern Med

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Background Methicillin-resistant Staphylococcus aureus (MRSA) causes serious infections in hospitals. Penthorum chinense Pursh (PCP), employed by the Miao ethnic minority in China, presents antibacterial activities. In this study, the anti- Staphylococcus aureus activities in the pinocembrin-7-O residue-rich fraction from PCP (PGF) were evaluated and characterized. Methods The PGF was prepared with 70% ethanol reflux extraction followed by fractional extraction and column chromatography. Pinocembrin-7-O residue components were identified with electrospray ionization mass spectrometry (ESI-MS). Anti- S. aureus activities of the fraction and the main components were evaluated in vitro with serially diluted microbroth assays. Cytotoxicity was evaluated with 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) chromogenic assays using the NCTC 1469 cell line. Results This study indicated that the PGF and three components (S1, S2, and S3) presented anti- S. aureus activities, including against clinically isolated MRSA strains. The molecular masses of S1, S2, and S3 were identical to those of pinocembrin-7-O-[4″,6″-hexahydroxydiphenoyl (HHDP)]-β-D-glucose, pinocembrin-7-O-[3″-O-galloyl-4″,6″-(s)-HHDP]-β-D-glucose, and Thonningianin A, respectively. The PGF, S1, S2, and S3 all presented an identical minimum inhibitory concentration (MIC) against S. aureus ATCC 25923 and ATCC 43300, which was 62.5 μg/mL. The minimum bactericidal concentrations (MBCs) of the PGF and S3 against ATCC 25923 were 125 and 250 μg/mL, and the MBCs of the PGF, S2, and S3 against ATCC 43300 were 250, 500, and 250 μg/mL, respectively. A time-kill assay consistently indicated that none of the bacterial clones of ATCC 25923 and ATCC 43300 could survive under 2× and 4× MIC PGF treatment for 24 h, respectively. In contrast, 10 4 CFU (colony-forming units) of ATCC 25923 and ATCC 43300 were killed by 8× and 4× MIC S3 within 24 h, respectively. Additionally, 1×, 2×, and 4× MIC the PGF presented similar postantibiotic effects (PAEs) on the strain ATCC 25923. However, the PAE of the PGF on the strain ATCC 43300 was concentration dependent (1× < 2× < 4× MIC). Finally, the PGF (200 μg/mL) and S3 (60 μg/mL) showed no cytotoxicity against human hepatoma cells. Conclusions The PGF and S3 from PCP present potential for the treatment of S. aureus and MRSA infections. The components S1 and S2 present inhibition activities against S. aureus .

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“…Devido suas propriedades mecânicas e coloração castanho-amarelado a marrom claro, seu emprego na indústria de pisos de madeira e construção civil são conhecidas. Estudos etnofarmacológicos e préclínicos demonstram que o óleo-resina e o óleo essencial obtido desta espécie apresentam atividades farmacológicas diversas (PEREIRA et al, 2019;REYES, 2020;SARTORI, [s.d. ]); nem como atividade antifúngica e antioxidante (TEIXEIRA DA SILVA et al, 2017).…”

Section: Staphylococcus Aureusunclassified

Caracterização Ópticas E Morfológicas De Filmes Biodegradáveis Compostos Por Fécula De Batata, Gelatina Bovina E Quitosana

Gonçalves¹,

Fontes²,

Assis³

et al. 2020

Desenvolvimento Social E Sustentável Das Ciências Agrárias 3

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EditoraDireitos para esta edição cedidos à Atena Editora pelos autores.Todo o conteúdo deste livro está licenciado sob uma Licença de Atribuição Creative Commons.Atribuição-Não-Comercial-NãoDerivativos 4.0 Internacional (CC BY-NC-ND 4.0). O conteúdo dos artigos e seus dados em sua forma, correção e confiabilidade são de responsabilidade exclusiva dos autores, inclusive não representam necessariamente a posição oficial da Atena Editora. Permitido o download da obra e o compartilhamento desde que sejam atribuídos créditos aos autores, mas sem a possibilidade de alterá-la de nenhuma forma ou utilizá-la para fins comerciais.A Atena Editora não se responsabiliza por eventuais mudanças ocorridas nos endereços convencionais ou eletrônicos citados nesta obra.Todos os manuscritos foram previamente submetidos à avaliação cega pelos pares, membros do Conselho Editorial desta Editora, tendo sido aprovados para a publicação.

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Evaluation of the antimicrobial and antioxidant activity of 7-hydroxy-4’, 6-dimethoxy-isoflavone and essential oil from Myroxylon peruiferum L.f

Cited by 8 publications

References 44 publications

Liquid and Vapor Phase of Four Conifer-Derived Essential Oils: Comparison of Chemical Compositions and Antimicrobial and Antioxidant Properties

Liquid and Vapor Phase of Four Conifer-Derived Essential Oils: Comparison of Chemical Compositions and Antimicrobial and Antioxidant Properties

Characterization of the anti-Staphylococcus aureus fraction from Penthorum chinense Pursh stems

Caracterização Ópticas E Morfológicas De Filmes Biodegradáveis Compostos Por Fécula De Batata, Gelatina Bovina E Quitosana

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