Evaluation of the antifertility activity of the broom<i>Spartium junceum</i>in the mammalian male

Baccetti, Baccio; Burrini, A. G.; Chen, J.S.; Collodel, Giulia; Giachetti, Daniela; Matteucci, Francesco; Menesini-Chen, M.G.; Moretti, Elena; Piomboni, Paola; Sensini, Cristiana

doi:10.1017/s0967199400001313

Cited by 6 publications

(1 citation statement)

References 7 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Spartium junceum is one of the medicinal plants that belong to the Fabacea family that was cultivated as ornamental plant [25], its flowers were used for the treatment of gastric ulcer in Turkey [26] it has miscellaneous functions as antioxidant, antifertility, simulator for uterine and GI contraction thus causing vomiting [27][28][29].…”

Section: Spartium Junceummentioning

confidence: 99%

In Vitro Evaluation of Antimicrobial potential of Some Medicinal Plants Extracted by Supercritical Fluid Extractor; Their Phytochemistry and GC-MS Analyses

Suleiman¹

2020

Preprint

View full text Add to dashboard Cite

BackgroundAlong with swift economy upgrowing and continuous amelioration of lifestyle, people at present are paying more attention to health issues. Synthetic drugs will be compensated with other natural ones which belong to natural origin. Plants have always been considered as sources of several compounds that are used in many fields, especially human and animal health, starting from boosting the immunity to treatment of infectious diseases caused by some pathogenic microbes such as bacteria, fungi as well as viruses. This study aimed to incorporate some types of plants within antimicrobial portfolio through examination of different six plants which were Cichorium intybus, Cinnamomum camphora, Commiphora myrrha, Foeniculum vulgare, Nerium oleander and Spartium junceum. As well, attempting to identify the active constituents of their extracts using GC-MS.Materials and MethodsAll selected plants were analyzed to determine their phytochemical composition such as phenolics, alkaloids, flavonoids, terpenoids, and so on. Extraction step was done by sophisticated equipment called supercritical fluid extractor SFE through adjustment of specific conditions include temperature, time, flow rate and pressure to change the behavior of CO2. Testing the antimicrobial activity of each plant extract via agar well diffusion method through formation of clear zones against wide range of pathogenic test microorganisms including both Gram positive and negative bacteria as well as yeasts. Finally, attempting to identify primarily the constituents of each plant extract using GC-MS.Results and Discussioncrude extract of F. vulgare showed the highest potency against C. albicans, E. faecalis and S. typhimurirm, it contains some unique compounds such as squalene, eugenol and isoeugenol while, Extract of Cichorium intybus showed a moderate activity especially against C. libolytica and MRSA and it includes Vitamin A like compound which indicates antioxidant property.ConclusionConclusively, fennel gave a promising result as a good wide spectrum antimicrobial agent because it contains some compounds act as antimicrobial agents such as eugenol which was used as food preservative in addition to squalene which acts as antioxidant and antimycotic agent so, it will be useful especially while it was used in highly purified form excluding all undesirable subcomponents.

show abstract

Section: Spartium Junceummentioning

confidence: 99%

In Vitro Evaluation of Antimicrobial potential of Some Medicinal Plants Extracted by Supercritical Fluid Extractor; Their Phytochemistry and GC-MS Analyses

Suleiman¹

2020

Preprint

View full text Add to dashboard Cite

show abstract

Transformation of 5-hydroxymethylfurfural to 5-hydroxymethyl-2-furan carboxylic acid mediated by silver nanoparticles biosynthesized from Spartium junceum flower extract

Ghamari Kargar,

Shafiei,

Bagherzade

2024

Materials Today Sustainability

View full text Add to dashboard Cite

Correlation between male fertility and acrosin-like protease activity in rats treated withspartium junceum

Chen

Menesini-Chen

Giachetti

et al. 1993

Zygote

Self Cite

View full text Add to dashboard Cite

Intraperitoneal injections of extracts of Spartium junceum in adult male rats were shown to reduce the rate of fertility and acrosin enzyme activity. For the latter the drug effects could be divided into two phases: in the first stage a significant increase in proteolytic activity was observed in all experimental animals examined; and in the second stage, there was a general decrease of up to 50% in enzyme hydrolytic properties. There is a notable difficulty in correlating the acrosin activity and the data obtained from mating tests. The effect of drugs on the activity of another acrosomal protease, benzamidine-resistant protease, was assayed. A significant decrease in this enyme was noted though the modality was different from that of acrosin. Extrapolating the data of the two co-extracted acrosomal proteases, the ratio of acrosin-like protease [E] and benzamidine-resistant protease [E]x, it was possible to correlate the value expressed to the rate of pregnancy. The implications of this finding is discussed although the exact molecular basis of the phenomenon is uncertain.

show abstract

Evaluation of the antifertility activity of the broomSpartium junceumin the mammalian male

Cited by 6 publications

References 7 publications

In Vitro Evaluation of Antimicrobial potential of Some Medicinal Plants Extracted by Supercritical Fluid Extractor; Their Phytochemistry and GC-MS Analyses

In Vitro Evaluation of Antimicrobial potential of Some Medicinal Plants Extracted by Supercritical Fluid Extractor; Their Phytochemistry and GC-MS Analyses

Transformation of 5-hydroxymethylfurfural to 5-hydroxymethyl-2-furan carboxylic acid mediated by silver nanoparticles biosynthesized from Spartium junceum flower extract

Correlation between male fertility and acrosin-like protease activity in rats treated withspartium junceum

Contact Info

Product

Resources

About