Evaluation of the antibacterial and physical properties of glass ionomer cements containing chlorhexidine and cetrimide: An in-vitro study

Deepalakshmi, Mohanavelu; Poorni, Saravanan; Miglani, Revathi; Indira, R; Ramachandran, S

doi:10.4103/0970-9290.74217

Cited by 41 publications

(67 citation statements)

References 1 publication

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…It was observed that when the adding amount of the antimicrobial agents was 1 wt%, the physical characteristics was the best through measurements of their setting times and determination of their compressive strength 74) . In a similar study, Chlorhexidine diacetate (CHX) and cetrimide (CT) were added to Fuji IX at 1 and 2% w/w ratio by Deepalakshmi et al The results have shown that experimental Fuji IX containing CHX and CT were effective in inhibiting L.casei, and incorporation of 1% CT was optimal to possess the appropriate antibacterial and physical properties by the agar diffusion test and the compressive strength 75) . Besides that, the antibacterial activity, microhardness numbers (VHN), and cumulative fluoride releasing (CFR) patterns of conventional GICs (Fuji IX and Ketac Molar) containing CHX/CT (2.5/2.5%) were evaluated by Tüzüner et al The results showed that modified GICs had antibacterial effect to S.mutans and L.casei, and there were no significant differences for CFR between modified GICs and no modified GICs, but VHN decreased significantly for modified GICs 76) .…”

Section: Glass Ionomer Cementmentioning

confidence: 99%

Quaternary ammonium compounds in dental restorative materials

Zhang

Chen

et al. 2018

Dent. Mater. J.

View full text Add to dashboard Cite

Quaternary ammonium compounds (QACs) have been used widely in medicine, owing to their antimicrobial properties. They also have strong permeability, stable performance, low skin irritation, low toxicity, low corrosion, lasting biological effects and so on, comparing with other antimicrobial agents. At the end of last century, polymerizable quaternary ammonium antimicrobial monomers had been synthesized and applied in dentistry, in order to reduce or prevent microbial biofilm formation on dental materials surfaces. This review aims to discuss the current progress of QACs applied in composite resin, adhesive systems, acrylic resin, glass ionomer cement and endodontic materials, regarding to their antimicrobial potential, mechanical properties, and biocompatibility.

show abstract

Section: Glass Ionomer Cementmentioning

confidence: 99%

Quaternary ammonium compounds in dental restorative materials

Zhang

Chen

et al. 2018

Dent. Mater. J.

View full text Add to dashboard Cite

show abstract

“…Also, addition of the antibiotics, such as metronidazole, ciprofloxacin, and cefaclor, can give rise to possible antibiotic resistance. 3 These limitations can be overcome by incorporating a herbal antibacterial agent to the GIC cement. Natural products have been used for thousands of years in folk medicine, and they are believed to be the new source of antibacterial agents.…”

Section: 22mentioning

confidence: 99%

Section: 22mentioning

confidence: 99%

“…Previously, in the scientific literature, efforts have been made to improve the antibacterial effect of GIC by incorporating CHX, 2,3,23,24 antibiotics, 25 xylitol, 24 and cetrimide. 3 Incorporation of these agents improved the antimicrobial effect of the GIC on cariogenic microorganisms. 26 However, Takahashi et al 27 concluded that incorporation of CHX diacetate at 2% or greater concentration significantly decreased compressive strength and bond strength of GIC.…”

Section: 22mentioning

confidence: 99%

“…Studying the physical properties combined with the antimicrobial effect after adding those agents is a valuable approach. 2,3 These limitations can be overcome by the addition of an herbal antibacterial extracts. Among the plants, studied Cinnamomum zeylanicum Blume (cinnamon) is one of the most effective antibacterial agents.…”

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Antimicrobial Efficacy of Cinnamon Bark Oil on Lactobacillus acidophilus and its Effect on Compressive Strength of Glass Ionomer Cement

Bhanushali¹

2017

World Journal of Dentistry

View full text Add to dashboard Cite

Aim:The aim of this study is to evaluate the minimum inhibitory concentration (MIC) of cinnamon bark oil against Lactobacillus acidophilus and incorporate it in the liquid component of glass ionomer cement (GIC) followed by determination of its effect on the compressive strength. Materials and methods:Antibacterial effect of various concentrations of cinnamon bark oil was evaluated using broth microdilution method with 96-well tissue culture plate. Minimum inhibitory concentration of the cinnamon bark oil against L. acidophilus was determined and that concentration was then incorporated into the liquid component of the GIC, and its compressive strength was evaluated. For compressive strength testing, teflon mold of 4 mm diameter and 6 mm height was used for the preparation of samples. The prepared specimens were stored in distilled water at 37°C for 24 hours in an incubator. After 24 hours, the samples were subjected to the universal testing machine at a speed of 1 mm/minute for compressive strength evaluation. The maximum load required to fracture the specimen was recorded.Results: A volume of 20 µL/mL was found to be the MIC of the cinnamon bark oil against L. acidophilus. The mean compressive strengths of conventional and cinnamon bark oil-incorporated GIC revealed no significant difference. Conclusion:Cinnamon bark oil has antibacterial property against L. acidophilus. Incorporation of 2% v/v cinnamon bark oil did not adversely affect the compressive strength of GIC.Clinical significance: By incorporating this bacteriostatic agent to GIC, the progress of caries and failure of restorations can be prevented by inhibiting the growth of L. acidophilus. Clinically, it can be used in cases of deep dentinal caries, early childhood caries, rampant caries, and patients with high caries index.

show abstract

Evolution of Anticariogenic Resin‐Modified Glass Ionomer Cements

Malik

Butt

et al. 2021

ChemBioEng Reviews

View full text Add to dashboard Cite

With advancing technology and exponential growth in scientific research, new perspectives in dental materials are being discovered. Conservative dentistry advocates maximum tooth preservation by revised restorative materials. Resin‐modified glass ionomer cement (RMGIC) is a flexible group of dental materials that can be used for restoring, lining, luting, and sealing teeth. Much advancements have been achieved to make them inherently anticariogenic as an adjunct to their fluoride release. In an attempt to resolve issues of secondary caries, white spot lesions, and cavitation, nanoparticles of metals such as zinc, silver, and titanium have been added. Biomaterials with regenerative potential like bioactive glass and hydroxyapatite are being explored as well. Similarly, antibiotics and natural resins like propolis and chlorhexidine have shown tremendous response against caries causing the oral pathogen Streptococcus mutans. This comprehensive review sheds light on the recent research in RMGIC, contemplating the repercussions of incorporating antibacterial agents into these types of cement.

show abstract

Evaluation of the antibacterial and physical properties of glass ionomer cements containing chlorhexidine and cetrimide: An in-vitro study

Abstract: The present study demonstrated that experimental GICs containing chlorhexidine diacetate and cetrimide were effective in inhibiting bacteria associated with caries, and incorporation of 1% cetrimide was optimal to give the appropriate antibacterial and physical properties.

Cited by 41 publications

References 1 publication

Quaternary ammonium compounds in dental restorative materials

Quaternary ammonium compounds in dental restorative materials

Antimicrobial Efficacy of Cinnamon Bark Oil on Lactobacillus acidophilus and its Effect on Compressive Strength of Glass Ionomer Cement

Evolution of Anticariogenic Resin‐Modified Glass Ionomer Cements

Contact Info

Product

Resources

About