Evaluation of the accuracy of dose delivery in stereotactic radiotherapy using the Velocity commercial software

Czajkowski, Paweł; Piotrowski, Tomasz

doi:10.1016/j.ejmp.2022.02.005

Cited by 4 publications

(5 citation statements)

References 32 publications

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“…Cole et al showed that the dose distributions on the deformed CT and replan CT matched closely 21 . And for stereotactic radiotherapy of lung cancer, differences between D 99 of the ITV on pCT and rCT could reach ± 10%, due to inhomogeneous dose distributions 27 . In this study, the dose delivery accuracy of CTV, GTV, CTV-P and GTV-P was evaluated simultaneously.…”

Section: Discussionmentioning

confidence: 99%

“…Except for the spinal cord, significant differences in the dose received by other OARs were not detected. The volume of anatomical structures significantly influences the outcomes of registration, subsequently affecting the accuracy of contour propagation 27,28 . Notably, the DSC of GTV decreases when the target volume is less than 15 cc, ranged from 0.22 to 0.81.…”

Section: Discussionmentioning

confidence: 99%

“…Meanwhile, neither CTV nor GTV consistently achieves a CR value of 1, suggesting the potential for CTV and GTV to extend beyond the planning target volume (CTV-P and GTV-P) boundaries due to tumor motion. Previous studies employing 4DCT for internal target volume (ITV) delineation and www.nature.com/scientificreports/ subsequent expansion to PTV have demonstrated CR values approaching 1, attributed to the accurate capture of lung tumor motion range 27,29 . From a dosimetric standpoint, both CTV and GTV exhibit minimal dose discrepancies, generally below 3% and predominantly within 2%, which are clinically acceptable.…”

Section: Discussionmentioning

confidence: 99%

“…The volumes of original and deformed targets were utilized for assessing the fidelity of contour propagation for GTV and CTV. Evaluation criteria for the mobility of target volumes included the dice similarity coefficient (DSC) and coverage ratio (CR) 27 , which indicated the coverage ratio of the deformed CTV and GTV areas by the original PTV and GTV-P areas. The corresponding calculation formula is as follows:…”

Section: Methodsmentioning

confidence: 99%

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Evaluation of dose delivery based on deformed CT using a commercial software for lung cancer

Chen,

OuYang

et al. 2024

Sci Rep

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This study employed a commercial software velocity to perform deformable registration and dose calculation on deformed CT images, aiming to assess the accuracy of dose delivery during the radiotherapy for lung cancers. A total of 20 patients with lung cancer were enrolled in this study. Adaptive CT (ACT) was generated by deformed the planning CT (pCT) to the CBCT of initial radiotherapy fraction, followed by contour propagation and dose recalculation. There was not significant difference between volumes of GTV and CTV calculated from the ACT and pCT. However, significant differences in dice similarity coefficient (DSC) and coverage ratio (CR) between GTV and CTV were observed, with lower values for GTV volumes below 15 cc. The mean differences in dose corresponding to 95% of the GTV, GTV-P, CTV, and CTV-P between ACT and pCT were − 0.32%, 4.52%, 2.17%, and 4.71%, respectively. For the dose corresponding to 99%, the discrepancies were − 0.18%, 8.35%, 1.92%, and 24.96%, respectively. These differences in dose primarily appeared at the edges of the target areas. Notably, a significant enhancement of dose corresponding to 1 cc for spinal cord was observed in ACT, compared with pCT. There was no statistical difference in the mean dose of lungs and heart. In general, for lung cancer patients, anatomical motion may result in both CTV and GTV moving outside the original irradiation region. The dose difference within the original target area was small, but the difference in the planning target area was considerable.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Methodsmentioning

confidence: 99%

See 2 more Smart Citations

Evaluation of dose delivery based on deformed CT using a commercial software for lung cancer

Chen,

OuYang

et al. 2024

Sci Rep

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show abstract

“…One of the methods to reduce inaccuracies of dose recalculation is based on the use of CBCT images to transform the CT images used in planning. The dose, in this method, is recalculated on transformed CT images [ 22 ]. Unfortunately, the prospective nature of our study, and the lack of availability to clinically approved DG procedures in our hospital in the years from 2012 to 2016, led to image guidance procedures being used during the treatment only.…”

Section: Discussionmentioning

confidence: 99%

Dosimetric Comparison of Ultra-Hypofractionated and Conventionally Fractionated Radiation Therapy Boosts for Patients with High-Risk Prostate Cancer

Piotrowski

Yartsev

Krawczyk

et al. 2022

Life

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Recent comparison of an ultra-hypofractionated radiotherapy (UF-RT) boost to a conventionally fractionated (CF-RT) option showed similar toxicity and disease control outcomes. An analysis of the treatment plans for these patients is needed for evaluating calculated doses for different organs, treatment beam-on time, and requirements for human and financial resources. Eighty-six plans for UF-RT and 93 plans for CF-RT schemes were evaluated. The biologically equivalent dose, EQD2, summed for the first phase and the boost, was calculated for dose-volume parameters for organs at risk (OARs), as well as for the PTV1. ArcCHECK measurements for the boost plans were used for a comparison of planned and delivered doses. Monitor units and beam-on times were recorded by the Eclipse treatment planning system. Statistical analysis was performed with a significance level of 0.05. Dosimetric parameter values for OARs were well within tolerance for both groups. EQD2 for the PTV1 was on average 84 Gy for UF-RT patients and 76 Gy for CF-RT patients. Gamma passing rate for planned/delivered doses comparison was above 98% for both groups with 3 mm/3% distance to agreement/dose difference criteria. Total monitor units per fraction were 647 ± 94 and 2034 ± 570 for CF-RT and UF-RT, respectively. The total delivery time for boost radiation for the patients in the UF-RT arm was, on average, four times less than the total time for a conventional regimen with statistically equal clinical outcomes for the two arms in this study.

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In vivo EPID-based daily treatment error identification for volumetric-modulated arc therapy in head and neck cancers with a hierarchical convolutional neural network: a feasibility study

Zeng,

Li,

Chang

et al. 2024

Phys Eng Sci Med

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Evaluation of the accuracy of dose delivery in stereotactic radiotherapy using the Velocity commercial software

Cited by 4 publications

References 32 publications

Evaluation of dose delivery based on deformed CT using a commercial software for lung cancer

Evaluation of dose delivery based on deformed CT using a commercial software for lung cancer

Dosimetric Comparison of Ultra-Hypofractionated and Conventionally Fractionated Radiation Therapy Boosts for Patients with High-Risk Prostate Cancer

In vivo EPID-based daily treatment error identification for volumetric-modulated arc therapy in head and neck cancers with a hierarchical convolutional neural network: a feasibility study

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