“…The cleft lip and palate (CLP) are the most common congenital malformations of the craniofacial region, with an incidence of 1 per 700 live births. Prevalence can be affected by sex, race, ethnic groups, geographical regions, and socioeconomic conditions [ 1 , 2 , 3 ]. The etiology of CLP is multifactorial, involving genetic and environmental factors, namely smoking consumption and ionizing radiation [ 2 , 4 , 5 , 6 ].…”