Evaluation of tea tree oil quality and ascaridole: A deep study by means of chiral and multi heart-cuts multidimensional gas chromatography system coupled to mass spectrometry detection

Evaluation of fast enantioselective multidimensional gas chromatography methods for monoterpenic compounds: Authenticity control of Australian tea tree oil

“…This alters the quantity of compound sampled. It was observed that EFs are negligibly affected by analyte quantity, which is in agreement with a report by Sciarrone et al [14], however, it should be noted that for low abundance components (in this case limonene and ␣-terpineol), maximum transfer of each component is favoured. Overall, the proposed GC-eGC method achieved interference-free enantioseparation of the analytes of interest in less than 25 min.…”

Enantiomeric distribution of selected terpenes for authenticity assessment of Australian Melaleuca alternifolia oil

“…In this respect, several studies have demonstrated chiral analysis of TTO using different enantioselective approaches such as gas chromatography (GC), heart-cutting multidimensional GC (GC-GC) and comprehensive two-dimensional GC (GC × GC) (Kreck et al, 2002;Leach et al, 1993;Sciarrone et al, 2010;Shellie et al, 2001). However, previous work largely focused on either method or instrumental development for reliable enantiomeric assays, or did not address an industry-wide reference-point for TTO composition so data were inconclusive in establishing a baseline enantiomeric composition for 100% pure Australian TTO.…”

A phytochemical of modern medicinal perspective

“…Chromatography and extraction methods including chiral chromatography were used in this study because of the stereospecificity. During the storage, there is the chance of some alteration in the chemical profile of this oil and formation of endoperoxides, peroxides, 1,2,4-trihydroxymenthane, ascaridole and alterations of other components due to oxidative reactions if proper attentions have not been paid [31]. For simultaneous determination of ascaridole and other phytochemicals in rat plasma, gas chromatography-mass spectrometer (GC-MS) technique was developed and validated.…”

“…For the detection of ascaridole in the Australian tea tree oil (Melaleuca alternifolia), multi heart-cut multidimensional gas chromatographic system coupled with mass spectrometer and by conventional enantio-GC were used and further method validation was also carried out for monitoring the repeatability of the traditional one-dimensional peak detection, routine application, two-dimensional peak detection, limit of detection and limit of quantification [31]. GC and GC-MS chemical profiling of the hydrodistilled volatile oil from Tanacetum macrophyllum and Achillea grandifolia Friv through Clevenger-type apparatus revealed the identification of more than 215 components.…”