Evaluation of systemic Inflammatory response markers in patients with preeclampsia

Abstract

Objective The neutrophil lymphocyte ratio (NLR), platelet lymphocyte ratio (PLR), and mean platelet volume (MPV) are all indicators of systemic inflammatory response. The goal of this study was to assess changes in NLR, PLR, and MPV in preeclampsia (PE) and their use in predicting its severity. Methods This is a case-control study that was conducted in the past. The research included 140 healthy pregnant women as controls and 60 women with PE. These two groups were compared using demographic information as well as inflammatory indicators. Results There were no statistically significant variations in hemoglobin, gravida, parity, platelets, NLR, PLR, and MPV between healthy pregnant females and preeclamptic females (P > 0.05). In contrast, we discovered statistically significant differences in mean age, lymphocytes, and neutrophils between the control group and PE patients (P < 0.05). Conclusion Prospective multicenter studies are also required to determine the relationship between these indicators and PE.