Evaluation of Some Redox Mediators in the Design of Reagentless Amperometric Glucose Biosensor

Kausaitė-Minkstimienė, Asta; Mazeiko, Viktor; Ramanavičienė, Almira; Öztekin, Yasemin; Solak, Alı Osman

doi:10.1002/elan.201400023

Cited by 24 publications

(7 citation statements)

References 39 publications

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“…Diabetes mellitus is a group of diseases, characterized by disorders of insulin secretion. 1 Nowadays the amount of people who have diabetes mellitus is growing and it is prognosticated that by 2035 more than 592 million people in the world will have this disease. 2 The early diagnosis of diabetes mellitus is an important way what can help to protect people who have this disease from complication of diabetes mellitus.…”

mentioning

confidence: 99%

Amperometric Glucose Biosensor Based on Titanium Electrode Modified with Prussian Blue Layer and Immobilized Glucose Oxidase

Valiūnienė

Virbickas

Rekertaitė

et al. 2017

J. Electrochem. Soc.

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In this paper amperometric glucose biosensors based on titanium (Ti) electrode coated with Prussian blue (PB) layer and immobilized glucose oxidase (GOx) is reported. Several techniques of PB layer deposition and immobilization of GOx were applied in order to find the most optimal design of biosensor. PB layer was formed by electrochemical PB deposition on titanium electrode in FeCl 3 and K 3 [Fe(CN) 6 ] solution. GOx was immobilized on PB layer using two techniques: immobilization by electrochemical polymerization of pyrrole and fixation with vapor of glutaraldehyde. The designed biosensors displayed sensitivity toward glucose in the range from 0.19 to 3.87 μA cm −2 mM −1 .

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confidence: 99%

Amperometric Glucose Biosensor Based on Titanium Electrode Modified with Prussian Blue Layer and Immobilized Glucose Oxidase

Valiūnienė

Virbickas

Rekertaitė

et al. 2017

J. Electrochem. Soc.

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“…The catalytic performance of CNT-AuNP-GOx bioanodes with the involvement of TTF was investigated by cyclic voltammetry (CV). Figure C showed that when glucose was present, the intensity of the oxidation current of TTF increased obviously, with the onset oxidation potential around −0.06 V. ,, It was consistent with the result of the open circuit potential measurement.…”

Section: Resultsmentioning

confidence: 99%

Carbon Nanotube-Gold Nanoparticle-Based Self-Powered Electrochemical Biosensors for Highly Sensitive and Stable Detection of Myoglobin

Zhu

Sun

Yin

et al. 2023

ACS Appl. Nano Mater.

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A convenient and ultrasensitive self-powered aptasensing device based on an enzymatic biofuel cell (EBFC) was developed for myoglobin (Mb) detection. The self-powered aptasensor was composed of a functionalized biocathode with carbon nanotube-gold nanoparticle-aptamer (CNT-AuNP-aptamer) and a bioanode with carbon nanotube-gold nanoparticleglucose oxidase (CNT-AuNP-GOx). To ensure the performance of the self-powered aptasensor, the CNT-AuNP hybrid was selected as the electrode material because of its excellent biocompatibility, superior electrical conductivity, and chemical stability. Meanwhile, aptamer was assembled onto the CNT-AuNP functionalized biocathode through the Au−S bond. When the Mb was present, the aptamer could capture it on the biocathode via specific recognition, and the significant steric hindrance efficiently blocked the electronic transport for the redox probe [Fe(CN) 6 ] 3− at the biocathode, which caused a dramatic decrease of the open-circuit voltage (E OCV ). Promisingly, this self-powered aptasensor has particularly high sensitivity for Mb detection over a wide concentration spectrum of 0.1−1 × 10 4 ng mL −1 ; the detection limit is as low as 0.011 ng mL −1 (S/N = 3), and the sensor has excellent selectivity, reproducibility, and stability. In addition, the results of the relative standard deviation (RSD) (3.19−5.34%) and recovery (99.27−101.34%) indicated that the aptasensor can be applied to accurately assay Mb within complex biological matrices. As in situ Mb monitoring is of crucial clinical diagnostic significance, this work not only provides an intelligent method for ultrasensitive biosensing of Mb but also is a prospective prototype for a portable and in situ biomedical sensor.

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“…Premodification of the electrodes with PANI nanostructures and rGO also led to an increase in the K Mapp . value from 12.0 ± 1.9 mM (GR/GOx) to 77.7 ± 9.5 mM and 30.5 ± 4.9 mM, respectively, which also testifies to a wider linear range of biosensors [ 44 ]. A higher Δ I max value of the biosensor based on a GR/rGO/GOx (78.7 ± 5.2 μA) electrode in comparison to a GR/PANI/GOx electrode (44.8 ± 2.7 μA) could be related to better electron transfer through the matrix.…”

Section: Resultsmentioning

confidence: 99%

Reduced Graphene Oxide and Polyaniline Nanofibers Nanocomposite for the Development of an Amperometric Glucose Biosensor

Popov

Aukštakojytė

Gaidukevič

et al. 2021

Sensors

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The control of glucose concentration is a crucial factor in clinical diagnosis and the food industry. Electrochemical biosensors based on reduced graphene oxide (rGO) and conducting polymers have a high potential for practical application. A novel thermal reduction protocol of graphene oxide (GO) in the presence of malonic acid was applied for the synthesis of rGO. The rGO was characterized by scanning electron microscopy, X-ray diffraction analysis, Fourier-transform infrared spectroscopy, and Raman spectroscopy. rGO in combination with polyaniline (PANI), Nafion, and glucose oxidase (GOx) was used to develop an amperometric glucose biosensor. A graphite rod (GR) electrode premodified with a dispersion of PANI nanostructures and rGO, Nafion, and GOx was proposed as the working electrode of the biosensor. The optimal ratio of PANI and rGO in the dispersion used as a matrix for GOx immobilization was equal to 1:10. The developed glucose biosensor was characterized by a wide linear range (from 0.5 to 50 mM), low limit of detection (0.089 mM), good selectivity, reproducibility, and stability. Therefore, the developed biosensor is suitable for glucose determination in human serum. The PANI nanostructure and rGO dispersion is a promising material for the construction of electrochemical glucose biosensors.

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Evaluation of Some Redox Mediators in the Design of Reagentless Amperometric Glucose Biosensor

Cited by 24 publications

References 39 publications

Amperometric Glucose Biosensor Based on Titanium Electrode Modified with Prussian Blue Layer and Immobilized Glucose Oxidase

Amperometric Glucose Biosensor Based on Titanium Electrode Modified with Prussian Blue Layer and Immobilized Glucose Oxidase

Carbon Nanotube-Gold Nanoparticle-Based Self-Powered Electrochemical Biosensors for Highly Sensitive and Stable Detection of Myoglobin

Reduced Graphene Oxide and Polyaniline Nanofibers Nanocomposite for the Development of an Amperometric Glucose Biosensor

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