Evaluation of some immunological markers related to immune anergy in tuberculosis patients

Abstract

This study was applied on 90 tuberculosis patients admitted in the Babylon Center of Tuberculosis and Chest Diseases in Hilla, Iraq. They were divided into four groups; 50 patients with Pulmonary, 40 patients with Extra pulmonary,20 people as healthy contact group and 20 people as healthy control group. Blood samples were collected from patients and control group to estimate Anti Ascrais lumbricoides-IgG , also Zinc and copper level were also spectrophotometerically estimated. The ages range of all TB cases were ranged from 11 to more than 71 years; TB patients consisted of 51 males and 39 females. The mean of Anti- Ascrais lumbricoides IgG in PTB patient's sera was 0.43±0.17, while in control subjects was 0.20±0.19. The study significantly shows difference between PTB patients and controls, while The mean of anti Ascrais lumbricoides IgG in EPTB patients sera was 0.23±0.02, while in control subjects was0.20±0.19. The study significantly shows no difference between EPTB patients and controls.