“…Anion exchange resins performed well as disintegrant for basic drugs so as to avoid ionic binding between resin and drug. 66 Factors Affecting the Performance of Disintegrants Factors affecting the performance of a disintegrant include its particle size, methods of disintegrant incorporation especially for wet granulation, applied compression force, moisture content, and reworking. 67 Changes in the particle size of a disintegrant can affect its performance as a tablet disintegrant.…”
“…Anion exchange resins performed well as disintegrant for basic drugs so as to avoid ionic binding between resin and drug. 66 Factors Affecting the Performance of Disintegrants Factors affecting the performance of a disintegrant include its particle size, methods of disintegrant incorporation especially for wet granulation, applied compression force, moisture content, and reworking. 67 Changes in the particle size of a disintegrant can affect its performance as a tablet disintegrant.…”
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