Evaluation of Solvent Effect (Methanol: Water Mixture) on the Phenolic Content and Antioxidant Activities of Stachys turcomanica Trautv

Namvar, Khashayar; Mohammadi, Ameneh; Salehi, Esmail Ataei; Feyzi, Peyman

doi:10.15171/ps.2017.36

Cited by 12 publications

(6 citation statements)

References 33 publications

(31 reference statements)

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“…According to Ghimire et al (2011), the existence of bioactive chemicals such as phenolics, flavonoids, and tannins in different plant sections could reflect the varying scavenging activities. The perusal of available literature indicates a clear link between the radical scavenging ability of plant extracts and phytochemical contents (Arumugam et al, 2019(Arumugam et al, , 2020Namvar et al, 2017). The current findings also support the view of Yingming et al (2004), who found that extracts with a high phenolic content were more effective in scavenging free radicals.…”

Section: Dpph Radical Scavenging Ac Vitysupporting

confidence: 87%

Comparative antioxidant, antibacterial and phytochemical analysis of roots, stems, leaves and seeds from Cleome rutidosperma DC

Arumugam¹,

Balachandravinayagam²,

Jayakumar³

et al. 2022

NRFHH

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The emerging microbial infections and their resistance to the existing antibiotics lead to discovering novel compounds, primarily from medicinal plants with secondary metabolites having several bioactive potentials, including antioxidants. The current investigation aims to measure the antioxidant and antibacterial efficacy of ethanolic extracts from roots, stems, leaves and seeds of Cleome rutidosperma. The extracts were subjected to quantitative (total phenolic and flavonoid), qualitative phytochemical studies, and functional groups identification by FT-IR analysis. The extract of leaves showed the highest total antioxidant (54.21±1.56 mg ABAE/g), DPPH (62.92±1.94 mg GAEs/g), and FRAP (71.64±2.02 mg GAEs/g) activity among the all-tested parts. The antibacterial efficacy of extracts was determined by the microdilution bioassay method, which demonstrated that G(+ve) bacteria appear to be more susceptible to the crude extracts than G (-ve) bacteria. The qualitative phytochemical screening-detected alkaloids, flavonoids, phenols, sugars, proteins, saponins, sterols, tannins, and terpenoids. The leaves have the highest levels of phenolics (70.451.23 mg GAE/g DW) and flavonoids (32.261.12 mg RE/g DW) among the all-tested parts. The extracts' functional group was validated using the FT-IR spectra. Polyphenols, flavonoids, and tannins were identified in the crude extracts. These findings imply that C. rutidoserma could be a promising candidate for further research into infectious illness treatment and as a resource of novel antioxidants in nutraceutical and biopharmaceutical industries as a functional additive.

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Section: Dpph Radical Scavenging Ac Vitysupporting

confidence: 87%

Comparative antioxidant, antibacterial and phytochemical analysis of roots, stems, leaves and seeds from Cleome rutidosperma DC

Arumugam¹,

Balachandravinayagam²,

Jayakumar³

et al. 2022

NRFHH

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show abstract

“…37 Previously, a strong correlation has been observed between radical scavenging power of plant extract with total phenolics and flavonoids contents. 24 The present results provided evidence that most extracts with high contents of phenolics exhibited greater potency to scavenge free radicals. may also contribute to scavenging capacity.…”

Section: Discussionsupporting

confidence: 59%

“…23 Hence, a proper solvent system has to be used for extraction of maximum amounts of potent antioxidant components from typical plant materials. 24 On the one hand; medicinal plants produce secondary metabolites that are responsible for their therapeutic properties. On the other hand, quality and quantity of these molecules and conversely their activities are affected by environmental factors like geographical locations and origin of plants.…”

Section: Discussionmentioning

confidence: 99%

Antibacterial, antifungal and antioxidant activity of Cleome coluteoides: An In Vitro Comparative Study between Leaves, Stems, and Flowers

Moghaddam¹,

Mohammadi²,

Alesheikh³

et al. 2019

tjps

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Objective: Cleome coluteoides belongs to Capparidaceae family and has been used in folk medicine for a long time. The aim of our research was measuring the antioxidant, antibacterial and antifungal activities of C. coluteoides. Materials and Methods: different parts of plant were extracted by various solvents (ethyl acetate, methanol and dichloromethane). Antibacterial and antifungal activities were assayed by disk and well diffusion methods. The antioxidant activity was screened by DPPH and FRAP methods. Results: The results showed that Gram negative bacteria and fungus were resistant to various plant extracts. Flower extract of C. coluteoides had the highest inhibition effects against all of tested gram positive bacteria. Also, Bacillus cereus was the most sensitive bacteria with inhibition zone of 18 mm. In antioxidant activity assay, different extracts of C. coluteoides exhibited various antioxidant activities due to the physical and chemical properties of solvent. In a way that, methanol extract of leaves showed the highest DPPH radical scavenging activity at various concentrations ranged from 5-160 mg.ml-1. Among all tested extracts, the highest level of phenolics was observed in the methanol extract of flower. Discussion and Conclusion: this study demonstrates that different extracts from various parts of C. coluteoides are different in their properties, so a proper solvent would be used to extract maximum amounts of antioxidant and antibacterial components from a typical plant material.

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“…SP1's methanolic and 50% methanolic extracts exhibited higher AGI activity than its water extract (Table 1). Methanol has the ability to extract more secondary metabolites from plants, which were the target compounds in this analysis (Abarca-Vargas et al, 2016;Namvar et al, 2017). Previous research conducted on S. palustris also indicated that alkaloid and phenolic groups were possible compounds responsible for the plant's AGI activity (Chai et al, 2015;Leng, 2016).…”

Section: Impact Of Harvesting Technique and Extraction Solventmentioning

confidence: 92%

Post-harvest and Extraction Conditions for the Optimum Alpha Glucosidase Inhibitory Activity of Stenochlaena palustris

Gunawan-Puteri¹,

Kato²,

Rahmawati³

et al. 2021

IJTech

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Stenochlaena palustris has been studied for its anti-diabetic potency related to its alphaglucosidase inhibitory (AGI) activity. This study aimed to evaluate the impact of post-harvest and extraction conditions on the AGI activity of S. palustris and isolate the AGI bioactive principal component. AGI activity was calculated based on the inhibition of S. palustris samples against in vitro rat intestinal maltase and sucrase hydrolytic activities in enzymatic reactions. The selected extracts were subjected to activity-guided fractionation using liquid-liquid sequential separation, followed by silica N60 column chromatography. This study showed that post-harvest treatment significantly protected the AGI activity of S. palustris, while its optimum extract condition was observed with methanol and a smaller particle size (< 250 µm) at a sample to solvent ratio of 1:20 (w/v) for 24 h. Further fractionation, followed by Liquid chromatography-mass spectrometry (LC-MS) and proton nuclear magnetic resonance (NMR) evaluation of the S. palustris extracts from optimum postharvest and extraction conditions, also resulted in the identification of kaempferol 3-O-βglucopyranoside (astragalin) as the responsible bioactive AGI compound. This study's findings are expected to contribute to further study and utilization of S. palustris as an anti-diabetic agent based on its AGI activity.

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Evaluation of Solvent Effect (Methanol: Water Mixture) on the Phenolic Content and Antioxidant Activities of Stachys turcomanica Trautv

Cited by 12 publications

References 33 publications

Comparative antioxidant, antibacterial and phytochemical analysis of roots, stems, leaves and seeds from <i>Cleome rutidosperma</i> DC

Comparative antioxidant, antibacterial and phytochemical analysis of roots, stems, leaves and seeds from <i>Cleome rutidosperma</i> DC

Antibacterial, antifungal and antioxidant activity of Cleome coluteoides: An In Vitro Comparative Study between Leaves, Stems, and Flowers

Post-harvest and Extraction Conditions for the Optimum Alpha Glucosidase Inhibitory Activity of Stenochlaena palustris

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