Abstract:Over the past decade, single-use tangential flow filtration (TFF)
technologies have emerged to reduce system preparation time, promote
fast and flexible product change over, and ultimately shorten process
development and manufacturing time/cost. In this study, the performance
of a recently developed Pellicon® single-use TFF capsule was compared
against traditional Pellicon® cassette by assessing TFF process
performance (such as flux, residuals clearance, and yield) and
post-purification product attributes (suc… Show more
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