Evaluation of Silicone Elastomer Catheters for Long-term Intravenous Chemotherapy

IVI epoprostenol as salvage therapy in pulmonary arterial hypertension: an Australian perspective

“…Once practice changed to the use of single‐lumen catheters only, there were no cases of line‐related sepsis. These rates of infection are comparable with those reported elsewhere 22–25 . There was one incident involving the recall of prostacyclin cassettes across Australia, related to a faulty batch of cassettes identified by the manufacturer.…”

Peripherally Inserted Central Catheter (PICC) Complications During Pregnancy

“…Another factor thought to contribute to complication rates is duration of catheter use, but the available data are limited and inconclusive. In a review of 12 studies, Merrell et al 14 noted that the mean PICC duration studied is 20–50 days, and although other studies do include patients with PICCs in place for much longer periods (520 days in Legha et al 15 ; 210 days in Ogura et al 3 ), these studies do not stratify complication rates by duration of catheter. Moureau et al 10 found that more catheter‐related systemic infections occurred with longer duration of use (14% of sepsis cases in first week of PICC insertion, 15% in second week, 23% in third week, and 48% after 30 days).…”

Development of antimicrobial‐loaded polyurethane films for drug‐eluting catheters

“…Silicone resin turned out to be a promising material and appeared in several catheter studies. [6][7][8][9] Nonetheless, poor mechanical performance of silicone enhanced the interest in polyurethane-based catheters which have often proven superior performance over the silicone ones. 10,11 Polyurethane is generally synthesized from polyhydric alcohols and polyisocyanates 12 though newer nonisocyanate routes have been discovered.…”