Evaluation of Sexual Dysfunction in Females With Ankylosing Spondylitis

Abstract

Objectives: This study aims to evaluate sexual function in females with ankylosing spondylitis (AS), compare them with healthy controls, and demonstrate the effects of AS on female sexual functions. Patients and methods: Fifty-four AS patients (mean age 39.33±8.57 years; range 20 to 55 years) and 56 similar aged healthy controls were included in the study. Depression levels and sexual functions of all participants were evaluated by the Beck Depression Inventory and Female Sexual Function Index (FSFI), respectively. Other assessment methods included the visual analog scale for pain, fatigue, and importance of sexual life; Bath Ankylosing Spondylitis Disease Activity Index for disease activity, Bath Ankylosing Spondylitis Functional Index for functionality, Bath Ankylosing Spondylitis Metrology Index for spinal mobility, and Short Form-36 (SF-36) for quality of life. Results: Total FSFI and all FSFI subscale scores and number of weekly sexual intercourse were significantly lower while Beck Depression Inventory score was significantly higher in females with AS when compared to controls. In AS patients with depression, total FSFI score and FSFI subscales scores of desire and arousal were significantly lower than those without depression. In females with AS, there were negative correlations between total FSFI score and duration of complaint, Beck Depression Inventory score, Bath Ankylosing Spondylitis Metrology Index score, visual analog scale score, age, and duration of marriage while positive correlations existed between total FSFI score and visual analog scale importance of sexual life score and number of weekly sexual intercourse, SF-36 fatigue, SF-36 social function, SF-36 pain, and SF-36 mental component scores. Conclusion: Sexual dysfunction was more common in female AS patients without marked impairment in body image and hip involvement when compared to normal population. Sexual problems which are generally neglected should be handled regardless of disease activity when evaluating patients with AS and establishing a treatment plan.

Systematic Review of the Impact of Inflammatory Arthritis on Intimate Relationships and Sexual Function

“…Descriptive characteristics of the 55 included studies are summarised in Table 1. Of the included studies, 50 (90.1%) were quantitative, (7,9,19,27,(60)(61)(62)(63)(64)(65)(66)(67)(68)(69)(70)(71)(72)(73)(74)(75)(76)79,81,82,(84)(85)(86)(87)(88)(90)(91)(92)(93)(94)(96)(97)(98)(99)(100)(101)(102)(115)(116)(117)(118)(119)(120)(121) five (9.1%) were qualitative (77...…”

“…(8) Four of the qualitative studies used focus groups or semi-structured interviews, (80,83,89,95) while all the quantitative studies used patient-reported questionnaires. (7,9,19,22,27,(60)(61)(62)(63)(64)(65)(66)(67)(68)(69)(70)(71)(72)(73)(74)(75)(76)79,81,82,(84)(85)(86)(87)(88)(90)(91)(92)(93)(94)(96)(97)(98)(99)(100)(101)(102)(115)(116)(117)…”

“…(7,9,19,22,27,(60)(61)(62)(63)(64)(65)(66)(67)(68)(69)(70)(71)(72)(73)(74)(75)(76)79,81,82,(84)(85)(86)(87)(88)(90)(91)(92)(93)(94)(96)(97)(98)(99)(100)(101)(102)(115)(116)(117)(118)(119)(120)(121) Included studies were conducted, where reported, in the European Union (n=16; 29%), (8,19,…”

“…(74) Mean (SD) IA disease duration ranged from 3.3 (2.6) years to 19.0 (11.6), 52 (94.5%) studies reported participants had a disease duration of greater than five years. (7)(8)(9)19,27,(60)(61)(62)(63)(64)(65)(66)(67)(68)(69)(70)(72)(73)(74)(75)(76)(77)(79)(80)(81)(82)(84)(85)(86)(87)(88)(89)(90)(91)(92)(93)(94)(95)(96)(97)(98)(99)(100)(101)(102)(115)(116)(117)(118)…”

The importance of physiotherapy in the sexuality of patients with rheumatic diseases

“…Kobelt et al [ 12 ] found that age, sex, well-being, physical fitness, and mood were significant predictors of sexual activity in RA. Sexual dysfunction also correlated with pain, depressive mood, and degree of motor activity, and did not correlate with the BASDAI (Bath Ankylosing Questionnaire) – the main method of assessing the disease activity [ 18 ].…”