Evaluation of Serum and Tissue Levels of β-Carotene

Brandt, Richard B.; Kaugars, George E.; Riley, William T.; Dao, Quyen; Silverman, Sol; Lovas, John G.L.; Dezzutti, B. P.

doi:10.1006/bmmb.1994.1007

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1994

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Cited by 8 publications

(2 citation statements)

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“…The high incidence of low vitamin C concentrations in BMC may be due to a methodical error in the sample processing. In line with others [11,28,30], we found significantly high positive correlations between the AOX concentrations in blood plasma and BMC for vitamin E and ß-carotene.…”

Section: Discussionsupporting

confidence: 92%

Role of antioxidants in buccal mucosa cells and plasma on the incidence and severity of oral mucositis after allogeneic haematopoietic cell transplantation

Urbain

Raynor

Bertz

et al. 2011

Support Care Cancer

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Section: Discussionsupporting

confidence: 92%

Role of antioxidants in buccal mucosa cells and plasma on the incidence and severity of oral mucositis after allogeneic haematopoietic cell transplantation

Urbain

Raynor

Bertz

et al. 2011

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“…placed in 2-ml cryostat tubes and stored in a -70°C freezer until assay. Plasma and tissue vitamin E were quantified using an HPLC technique previously described (15,16). Table I shows plasma and liver vitamin E concentrations for mice on all diets.…”

Section: Methodsmentioning

confidence: 99%

Murine Red Blood Cell Fragility Is Not Affected by Either Vitamin E Depletion or Supplementation

Bei

Brandt

Rosenblum

et al. 1996

Experimental Biology and Medicine

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Male ICR mice were Pair-fed semipurified diets containing 0, 55 (control), and 500 IU/kg of vitamin E. Plasma and hepatic concentrations of vitamin E were determined and found to parallel the vitamin E levels in the diet. Even though plasma vitamin E levels were virtually zero in mice fed the depleted vitamin E diet for up to 304 days, there was no statistical difference in the red blood cell fragility between these animals and controls, as determined by a hypoosmotic fragility test. The diet with enriched vitamin E concentrations also did not affect the fragility of the red blood cell (RBC). Even after 300 days of zero dietary vitamin E, mice appeared healthy, demonstrating neither neurologic dysfunction nor failure to thrive. The data indicates that mice, unlike several other species, are more resistant to vitamin E depletion and may have other mechanisms to compensate for loss of this important antioxidant.

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Clinical development plan: β-Carotene and other carotenoids

1994

J. Cell. Biochem.

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Evaluation of Serum and Tissue Levels of β-Carotene

Cited by 8 publications

References 0 publications

Role of antioxidants in buccal mucosa cells and plasma on the incidence and severity of oral mucositis after allogeneic haematopoietic cell transplantation

Role of antioxidants in buccal mucosa cells and plasma on the incidence and severity of oral mucositis after allogeneic haematopoietic cell transplantation

Murine Red Blood Cell Fragility Is Not Affected by Either Vitamin E Depletion or Supplementation

Clinical development plan: β-Carotene and other carotenoids

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