Evaluation of serial QT dispersion in patients with first non‐Q‐wave myocardial infarction: Relation to the severity of underlying coronary artery disease

Lyras, Th.; Papapanagiotou, V. A.; Foukarakis, Masolis G.; Panou, Fotis; Skampas, Neoklis; Lakoumentas, John; Priftis, C. V.; Zacharoulis, Achilleas

doi:10.1002/clc.4960260409

Cited by 4 publications

(2 citation statements)

References 35 publications

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“…It is well known that the QT interval on standard 12-lead ECG is sensitive to myocardial ischaemia. Several studies have reported a relationship between increased QTc dispersion and CAD (28,29) . It has been known that ischaemic attacks lead to a temporary increase in QTcd in patients diagnosed with CAD (30) .…”

Section: Discussionmentioning

confidence: 99%

P-Wave and QT Dispersions on Electrocardiography in Coronary Artery Slow Flow Phenomenon

Korkmaz¹

2017

Kosuyolu Heart Journal

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Introduction: The purpose of this study was to analyse P-wave and QT dispersions on electrocardiography in patients with CSFP and compare the findings with those of patients with NCA. Patients and Methods:This study included a total of 82 patients (40 patients with NCA and 42 patients with CSFP). Coronary blood flow was calculated according to the thrombolysis in myocardial infarction (TIMI) frame count. Electrocardiograms were obtained at a rate of 50 mm/s and amplitude of 20 mV, including at least 3 QRS complexes for each derivation, and were taken with 12 standard deviations. The longest P-wave duration was defined as Pmax, and the shortest P-wave duration was defined as Pmin. The difference between Pmax and Pmin was defined as P-wave dispersion. QTc, which is the QT interval corrected for heart rate, was measured according to Bazett's formula. The difference between the longest QTc and shortest QTc was considered as QTc dispersion. All measurements were performed manually.Results: This study demonstrated that P-wave dispersion (53.2 ± 5.35 and 46.07 ± 4.12, p < 0.0001, respectively), Pmax (106.2 ± 10.11 and 97.7 ± 8.17, p< 0.0001, respectively), maximum QTc (438.96 ± 16.77 and 426.13 ± 10.01, p< 0.0001, respectively) and QTc dispersion (68.99 ± 4.34 and 61.64 ± 4.15, p< 0.0001, respectively) were significantly prolonged in the CSFP group than the NCA group. Conclusion:This study demonstrated that P-wave and QTc dispersions were prolonged in the CSFP group.Key Words: Coronary slow flow; P-wave dispersion; QTc dispersion Koroner Yavaş Akımda P Dalga Dispersiyon ve QTc Dispersiyonu ÖZET Giriş: Bu çalışmada koroner yavaş akım (KYA) tespit edilen hastalar ile normal koroner anatomi (NKA) tespit edilen hastalar arasında P dalga dispersiyonu ve QTc dispersiyonu karşılaştırıldı ve KYA ile P dalga dispersiyonu ve QTc dispersiyonu arasındaki ilişkinin belirlenmesi amaçlandı. Hastalar ve Yöntem:Çalışmaya 40 NKA ve 42 KYA olmak üzere toplam 82 hasta alındı. Koroner kan akımı TIMI kare sayısına göre hesaplandı. Elektrokardiyografi çekimleri her derivasyon için en az 3 QRS kompleksi içerecek şekilde, 50 mm/saniye hızında, 20 mV amplitüdünde ve standart 12 derivasyonda çe-kildi. En uzun p dalgası Pmax ve en kısa p dalgası Pmin olarak kabul edildi. En uzun P dalgası ile en kısa p dalgası arasındaki farkı P dispersiyonu kabul edildi. QTc dispersiyonu ölçümleri için öncelikle kalp hızına göre Bazzet formülü (QT/√R-R) ile düzeltilmiş QT aralığı hesaplandı. En uzun QTc aralığı (QTcmax) ile en kısa QTc (QTcmin) aralığı arasındaki fark hesaplanarak ölçüldü. Bütün ölçümler manuel olarak yapıldı. Bulgular: Bu çalışma KYA grubunda P dispersiyonu (sırası ile 53.2 ± 5.35 ve 46.07 ± 4.12, p< 0.0001), Pmax (sırası ile 106.2 ± 10.11 ve 97.7 ± 8.17, p< 0.0001), maksimum QTc (sırası ile 438.96 ± 16.77 ve 426.13 ± 10.01, p< 0.0001) ve QTc dispersiyonu (sırası ile 68.99 ± 4.34 ve 61.64 ± 4.15, p< 0.0001) sürelerinin NKA grubuna göre istatistiksel olarak anlamlı derecede uzun olduğunu göstermektedir.Sonuç: Bu çalışma koroner yavaş akı...

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Section: Discussionmentioning

confidence: 99%

P-Wave and QT Dispersions on Electrocardiography in Coronary Artery Slow Flow Phenomenon

Korkmaz¹

2017

Kosuyolu Heart Journal

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“…It has been shown previously that in patients with first non-Q-wave myocardial infarction, prolongation of QTd correlated with the severity of underlying CAD designated by the Duke Myocardial Jeopardy Score. 24 However, when atrial pacing was used during angiography, prolongation of QTd during stress positively correlated with severity of stenosis. 25,26 This discrepancy could be attributable to the difference in patient characteristics.…”

Section: Discussionmentioning

confidence: 99%

QT Dispersion at Rest and During Adenosine Stress Myocardial Perfusion Imaging Correlation with Myocardial Jeopardy Score

Vankayala²,

Niraj³

et al. 2008

Clinical Cardiology

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Background The usefulness of QT dispersion (QTd) during adenosine myocardial perfusion imaging (MPI) to predict severity of coronary artery disease (CAD) has not been studied. Methods Eighty‐eight patients referred for diagnostic cardiac catheterization after abnormal MPI were included. Thirty‐four patients with no stenosis (Duke Score = 0) were included in Group 1, and 54 patients with significant CAD (Duke Score ≥ 2) formed Group 2. Resting and stress QTd and prolongation in QTd (ΔQTd) were measured and evaluated as independent predictors for severity of CAD. Results Resting QTd was higher in Group 2 as compared with Group 1. During peak infusion of adenosine, QTd was significantly prolonged in Group 1 but remained unchanged, or fixed, in Group 2. In addition, in patients with significant CAD, resting QTd positively correlated with the Duke Score. On multiple regression analysis; independent predictors for significant CAD (odds ratio [OR], 95% confidence interval [CI], p‐value) were resting QTd (4.9, 95% CI 1.1–21.6, < 0.05 for fourth Quartile compared with first Quartile) and ΔQTd (4.0, 1.4–11.2, < 0.01 for first and second Quartiles compared with third and fourth Quartiles). Conclusion In patients with abnormal stress MPI, prolonged resting QTd, and fixation of QTd during stress are independent predictors of significant CAD. In addition, resting QTd correlate with the Duke Jeopardy Score and therefore, may have independent prognostic value. Copyright © 2008 Wiley Periodicals, Inc.

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Effects of coronary revascularization and concomitant aneurysmectomy on QT interval duration and dispersion

Koşar

Nisanoğlu

Aksoy

et al. 2006

Journal of Electrocardiology

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Evaluation of serial QT dispersion in patients with first non‐Q‐wave myocardial infarction: Relation to the severity of underlying coronary artery disease

Cited by 4 publications

References 35 publications

P-Wave and QT Dispersions on Electrocardiography in Coronary Artery Slow Flow Phenomenon

P-Wave and QT Dispersions on Electrocardiography in Coronary Artery Slow Flow Phenomenon

QT Dispersion at Rest and During Adenosine Stress Myocardial Perfusion Imaging Correlation with Myocardial Jeopardy Score

Effects of coronary revascularization and concomitant aneurysmectomy on QT interval duration and dispersion

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