Evaluation of semen quality in 1808 university students, from Wuhan, Central China

Abstract

The aim of this study was to evaluate the semen quality of university students in Wuhan, the largest city in the world in terms of the number of university students. All student sperm donors recorded in the Hubei Province Human Sperm Bank from 1 March 2010 to 31 December 2013 were screened. At last, a total of 3616 semen samples from 1808 university student sperm donors were eligible and retrospectively analyzed. Each donor's semen parameters were averaged over two samples and compared with the World Health Organization criteria, and a generalized linear regression model was used to examine several determinants of semen quality. We found that the mean and median values were 3.0 ml and 2.8 ml for semen volume, 50.2 × 106 ml−1 and 50.0 × 106 ml−1 for sperm concentration, 148.1 × 106 and 142.1 × 106 for total sperm count, and 58.6% and 60.0% for total sperm motility. About 85.0% of donors had parameters that were all normal. Season and duration of abstinence were critical factors affecting semen quality. We also found a decrease in sperm concentration during the 4 years observation; however, this may not be a strong evidence to confirm the declining trend of semen quality. In conclusion, semen quality of university students in Wuhan was not optimal and should be paid high attention, long-term observation and further study should be carried out to confirm the present situation.

Decline of semen quality among Chinese sperm bank donors within 7 years (2008-2014)

“…These trends continued to be present even after adjusting for age, BMI, duration of abstinence, and season. Compared with other similar Chinese studies, 23 24 25 26 most values for the semen parameters examined in our study ( Table 2 ) were in the middle of the other reported results. The probable reasons for this include: (1) the different criteria used to select participants; (2) regional differences; and (3) the different study periods.…”

“…Recently, Rao et al . 23 reported that in 1808 Wuhan University students, there was a decrease in sperm concentration during the 4-year observation (from 58.0 × 10 6 ml −1 in 2010 to 41.8 × 10 6 ml −1 in 2013). After adjusting for potential confounders (age, year, season, and duration of abstinence), sperm concentration and total sperm count also showed a tendency to decrease.…”

Efficacy and Outcome Predictors of Gonadotropin Treatment for Male Congenital Hypogonadotropic Hypogonadism

“…Patients in S subgroup had a sperm concentration of 11.7 (2.1, 24.4) million/mL at the end of follow-up and was lower than that of healthy Chinese young men (50.0 [36.0, 63.8] million/mL) ( P < 0.001). 13 The sperm progressive motility (A + B) ([36.9% ± 20.2%] vs [52.6% ± 11.2%], P < 0.001) and total mobility (A + B + C) ([44.4% ± 21.9%] vs [58.6% ± 11.1%], P < 0.001) were significantly lower than that of healthy young men (n = 1808, age ranges 22–30 years). 13 According to WHO reference values for human semen, 14 36% (51/143) of our patients attained normal sperm concentrations (≥15 million/mL).…”

“… 13 The sperm progressive motility (A + B) ([36.9% ± 20.2%] vs [52.6% ± 11.2%], P < 0.001) and total mobility (A + B + C) ([44.4% ± 21.9%] vs [58.6% ± 11.1%], P < 0.001) were significantly lower than that of healthy young men (n = 1808, age ranges 22–30 years). 13 According to WHO reference values for human semen, 14 36% (51/143) of our patients attained normal sperm concentrations (≥15 million/mL). Among them, only 67% (34/51) had normal sperm-progressive motility (A + B) (≥32%).…”

Cinsel perhiz süresi ve semen parametreleri arasındaki ilişki

“…Çeşitli çalışmalar, cinsel perhiz süresi ile sperm motilitesi arasındaki ters korelasyonun gösterildiği benzer sonuçlar bildirmiştir. [7,10,14,15,17,20,[34][35][36] Bununla birlikte, bazı çalışmalarda cinsel perhiz süresi ile motilite arasında herhangi bir korelasyon gözlenmemiştir. [11,12,17,22] Bu konuda görüş birliği bulunmamaktadır.…”