Evaluation of sealed vacuum extraction method (Seditainer) for measurement of erythrocyte sedimentation rate.

Patton, W. N.; Meyer, P.; Stuart, J.

doi:10.1136/jcp.42.3.313

Cited by 27 publications

(15 citation statements)

References 2 publications

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“…An example of this is the manual Seditainer system, which shows excellent correlation with the Westergren method and is currently established in the eye casualty department for near-patient testing. 6,7 Recently, a number of new automated ESR methods have become available which offer results within 25 min of venepuncture, combined with the added benefit of reduced operator workload.s,9 These are available in both laboratory and near-patient formats.…”

mentioning

confidence: 99%

Comparison of the erythrocyte sedimentation rate measured in the eye casualty department by the Seditainer method with an automated system

Browning

Burbidge

Hodgkins

1999

Eye

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Results Across the range of results from 1 to 120 mmlh, the correlation coefficient was 0.844.The automated method had a mean negative bias of -9.8 mmlh (95% confidence interval: -12.2 to -7.4 mmlh). The wide scatter of results produced limits of agreement (± 2 standard deviations) between the two methods of -45 to 26 mmlh. There were seven results that were underestimated by the automated system which were clinically significant. ConclusionsThere is a wide degree of scatter between the two sets of results. The automated system has a negative bias when compared with the manual method. There is a propensity for the automated system to sporadically underestimate the true result, sometimes to a degree that is clinically significant. The authors therefore cannot recommend replacement of the manual Seditainer system at the present time.

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confidence: 99%

Comparison of the erythrocyte sedimentation rate measured in the eye casualty department by the Seditainer method with an automated system

Browning

Burbidge

Hodgkins

1999

Eye

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“…The tubes used in the Seditainer ESR system have the advantage of wide diameter and the disadvantage of short length. 29 In our study, this disadvantage was most problematic in major inflammatory syndromes, with a decrease in the variation range of the highest Σ ESRs (Figure 3). The value of CRP variations in this situation is well established.…”

Section: Discussionmentioning

confidence: 51%

Σ Esr

Pawlotsky¹,

Goasguen

Guggenbuhl³

et al. 2004

Am J Clin Pathol

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The aim of the study was to simplify the first Sigma erythrocyte sedimentation rate (ESR) method (manual hematocrit adjustment to 0.35, sum of 4 sedimentation levels) and to confirm its clinical relevance. The erythrocyte sedimentation rate of undiluted blood samples from 576 patients was measured simultaneously with and without manual hematocrit adjustment to 0.35 to identify an approximate expression of the area under the curve and a formula for calculating the Sigma ESR. The Sigma ESR formula was based on the sum of 2 unadjusted sedimentation levels, at 30 and 60 minutes, together with the hematocrit value and the hemoglobin concentration. Sigma ESR values in 274 healthy subjects showed a gaussian distribution, no difference between men and women, and no significant increase with age. In recent-onset arthritis or disk-related lumbosciatic syndrome, Sigma ESR seemed to be a more reliable marker of inflammation than the Westergren ESR and C-reactive protein. We also obtained data clarifying the controversial relationship of ESR with lipid levels and arterial hypertension.

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“…A major drawback, however, is the short length of the tube that decreases the analytical sensitivity of the analysis. This can be counteracted by improved As shown in Figure 2 and by Patton et al [7], the conversion of readings of the 100-mm ESR at 60 rnin cannot be transformed to Westergren values by a simple linear model. This would overestimate low values and underestimate high values.…”

Section: Discussionmentioning

confidence: 95%

“…In a recent evaluation [7] of the vacuum-tube system, Patton et al summarized that the method offers a simple and safe technique for measuring the ESR. The robust design of the sedimentation vacuum tube also invites to the production of instruments for automatic reading of the ESR.…”

Section: Introductionmentioning

confidence: 97%

On the temporal development of erythrocyte sedimentation rate using sealed vacuum tubes

Kallner¹

1991

American J Hematol

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The temporal development of the erythrocyte sedimentation rate (ESR) was studied in wide, short vacuum tubes. It was found that in about 3% of the specimens arriving in the laboratory the ESR developed in three different phases during 60 min, whereas the other showed only two. The specimens with three phases behaved similarly in the Westergren method. It was shown that the Westergren ESR can be estimated with an acceptable accuracy already from measurements obtained after 30 min. Reproducibility and precision were improved by using a special instrument. Several advantages by this procedure were recognized, e.g., quicker results, identification of several otherwise missed rapid ESR. Accurate timing of the readings further improves accuracy and precision, and permits estimation of ESR (Westergren) up to 100 mm. In view of the obvious phases in the development of the ESR, it is proposed that this abbreviation is interpreted as erythrocyte sedimentation reaction and that the kind of quantity that is length is expressed in mm.

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Evaluation of sealed vacuum extraction method (Seditainer) for measurement of erythrocyte sedimentation rate.

Cited by 27 publications

References 2 publications

Comparison of the erythrocyte sedimentation rate measured in the eye casualty department by the Seditainer method with an automated system

Comparison of the erythrocyte sedimentation rate measured in the eye casualty department by the Seditainer method with an automated system

Σ Esr

On the temporal development of erythrocyte sedimentation rate using sealed vacuum tubes

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