Evaluation of scars in children after treatment with low-level laser

Abstract

Burn scars are known for their tendency to worsen with hypertrophy and contracture, causing esthetic and functional problems. The objective is to analyze the effectiveness of low-level laser therapy on post-burn hypertrophic scar tissue in children. A randomized controlled study included 15 children, ranging from 2 to 10 years of age, presented with post-burn hypertrophic scars. They received He-Ne laser and topical treatment. Each scar was divided into two halves. One half was treated with laser therapy and topical treatment (study area), and the other half was treated with topical treatment only (control area). The children were evaluated before, and after 3 months of the study by Vancouver Scar Scale (VSS), ultrasonography, and laser Doppler perfusion imaging. Significant improvement was reported in the studied area, compared to the control area for patients with P values (P = 0.003) and (P = 0.005), for VSS and U/S scores, respectively. No differences were detected for blood perfusion of the scar between both areas (P = 0.73). In addition, no adverse effects were reported. Photobiomodulation (PBM) is an efficient and safe therapeutic modality for post-burn hypertrophic scars in children, with no side effects, and should be considered a part of combination therapy for better results.

Effect of near‐infrared and blue laser light on vero E6 cells SARS‐CoV‐2 infection model

“…When considering the antiviral effect of NIR PBMT, few studies have been addressed this topic. NIR PBMT has been used to treat different human ailments in pediatric patients as oral mucositis wound [ 19 , 20 ], skin scars [ 21 ], and asthma [ 22 ]. The effect of NIR PBMT on virus was previously investigated by Donnarumma on HSV‐1 (830 nm) replication in the viral post‐absorption phase [ 18 ] and by our research group against Zika virus, both delivering PBMT on already infected cells and on the virus itself [ 17 ].…”

“…In this study a class IV laser medical device, commonly employed in the clinical practice in both adult and pediatric patients suffering oral mucositis wounds [ 19 , 20 ], skin scars [ 21 ], and asthma [ 22 ], was employed in a cell model of SARS‐CoV‐2 infection by using both the blue and the near‐infrared wavelengths.…”

Efficacy of pulsed dye laser combined with fractional CO2 laser in the treatment of pediatric burn scars

“…Despite the development of surgery techniques, the treatment of scars in pediatric patients is still a clinical challenge 19 . In recent years, laser techniques have been widely used to treat skin diseases, including in plastic surgery 20 . Numerous studies have demonstrated that PDL and fractional CO 2 laser have achieved obvious effects in the treatment of burn and trauma red hypertrophic scar 21–27 .…”

Evaluating the Effect of Low Power Diode Laser 806 nm on the Healing of Unilateral Cleft Lip Scar: An Open-Label Comparative Study

“…After three months, the studied scores (VSS and ultrasonography score) showed a significant improvement in the LLLT group compared with the control group (p = 0.003 and p = 0.005, respectively). In terms of the adverse effects, nothing was recorded (Alsharnoubi et al, 2018). Likewise, another RCT showed that LLLT was associated with a higher epithelization rate, wound-healing score, and color match score compared with the control group at free gingival graft donor sites (Ustaoglu et al, 2017).…”