Evaluation of Sandblasting on Mechanical Properties and Cell Response of Bioactive Glass Infiltrated Zirconia

Nguyen, Trung Hai; Oh, Gye Jeong; Lim, Hyun Pil; Yun, Kwi Dug; Kim, Ji Won; Vu, Van Thi; Park, Chan; Ban, Jae Sam; Yang, Hong; Park, Sang Won

doi:10.1166/jnn.2017.13329

Cited by 9 publications

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“…[ 7 9 , 10 ] Hence, studies focusing on surface treatments of zirconia to render the surface more receptive to osseointegration and apatite formation have gained significance. [ 9 11 ] However, t-m phase conversions after certain surface treatments that can deleteriously affect the longevity of zirconia as an implant biomaterial have also been reported,[ 1 ] and hence ascertaining maintenance of the tetragonal phase following any type of surface treatment of zirconia is crucial in bioactivity studies. Various reports are available stating the importance of surface topography and characteristics, such as surface roughness and wettability on the extent of bioactivity of zirconia,[ 1 2 , 11 ] following different surface treatments.…”

Section: Introductionmentioning

confidence: 99%

“…[ 9 11 ] However, t-m phase conversions after certain surface treatments that can deleteriously affect the longevity of zirconia as an implant biomaterial have also been reported,[ 1 ] and hence ascertaining maintenance of the tetragonal phase following any type of surface treatment of zirconia is crucial in bioactivity studies. Various reports are available stating the importance of surface topography and characteristics, such as surface roughness and wettability on the extent of bioactivity of zirconia,[ 1 2 , 11 ] following different surface treatments. Wettability has been suggested as a key parameter that impacts the chain of processes associated with osseointegration.…”

Section: Introductionmentioning

confidence: 99%

“…Thus, bioactivity studies also typically include surface characteristics investigations comparing untreated and treated zirconia surfaces to explain the bioactivity. [ 6 11 , 14 ] Methods such as X-ray diffraction (XRD), atomic force microscopy (AFM), contact angle goniometry, scanning electron microscopy (SEM), and energy dispersive X-ray spectroscopy (EDX) are used by researchers to assess crystal phase, roughness, wettability, topography, and elemental composition, respectively. [ 4 6 , 9 15 , 16 ]…”

Section: Introductionmentioning

confidence: 99%

“…Airborne particle abrasion known as sandblasting technique has been used to increase surface roughness of zirconia, which has been shown to positively impact osseointegration in cell culture studies. [ 9 11 , 17 19 ] One concern that is often mentioned is that sandblasting could result in damage to the zirconia surface, thereby altering the vital surface characteristics. Airborne particle abrasion with alumina particles lesser than 100 µm in size has been identified as a key factor in achieving an optimum surface roughness to enhance biological response of osteoblasts without causing structural damage to zirconia.…”

Section: Introductionmentioning

confidence: 99%

“…Airborne particle abrasion with alumina particles lesser than 100 µm in size has been identified as a key factor in achieving an optimum surface roughness to enhance biological response of osteoblasts without causing structural damage to zirconia. [ 9 11 , 18 20 21 22 ]…”

Section: Introductionmentioning

confidence: 99%

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Surface characteristics and bioactivity of zirconia (Y-TZP) with different surface treatments

et al. 2020

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A BSTRACT Background: Zirconia being a bio-inert material needs to be surface treated to render it more bioactive and enhance its osseointegration potential. However, bioactivity studies focusing on the ability of sandblasting and ultraviolet photofunctionalization (UVP) surface treatments in inducing apatite precipitation using simulated body fluid (SBF) are lacking. Aim: The aim of the study was to comparatively evaluate the effect of two different surface treatments—sandblasting with 50 µm alumina and UVP with ultraviolet C (UVC) light on the bioactivity of zirconia. Materials and Methods: A total of 33 discs with dimensions 10 mm × 2 mm were obtained from zirconia blanks (Amann Girrbach, Koblach, Austria) and randomly divided into three groups ( n = 11), namely Group I (untreated), Group II (sandblasted), and Group III (UVP). Surface characteristics of representative test samples were analyzed using X-ray diffraction (XRD), atomic force microscopy (AFM), contact angle goniometry, scanning electron microscopy (SEM), and energy dispersive X-ray spectroscopy (EDX), to assess type of crystal phase of zirconia, surface roughness, wettability, surface topography, and elemental composition, respectively. SBF was prepared and calcium content in SBF (Ca-SBF) was determined using inductively coupled plasma mass spectrometry (ICP-MS). Results: Data were analyzed by one-way analysis of variance (ANOVA), post hoc Tukey honestly significant difference (HSD), and Student’s t test for statistical significance ( P < 0.05, significant; P < 0.01, highly significant). Surface characteristics analyses revealed that XRD showed predominant tetragonal (t) zirconia crystal phase for all test groups. Mean surface roughness (Sa) of Group I was 41.83 nm, and it was significantly lesser than that of Group II (115.65 nm) and Group III (102.43 nm). Mean contact angles were 98.26°, 86.77°, and 68.03° for Groups I, II, and III, respectively, and these differences were highly significant. Mean pre-immersion Ca content in SBF was found to be 159 mg/L. Mean post-immersion Ca content was 70.10, 60.80, and 56.20 mg/L for Groups I, II, and III, respectively. Significant differences were found between Group I as compared to both Groups II and III. Bioactivity of Group III was marginally, but insignificantly higher with respect to Group II. Groups II and III were insignificant with respect to each other. Post-immersion XRD revealed predominant “t” phase, and SEM-EDX revealed well-formed, abundant calcium apatite layer on the treated samples as compared to that on untreated sample and an increasing Ca/P ratio from 1.15, 1.79 to 2.08, respectively from Group I to Group III. Conclusion: Within the limitations of this study, both sandblasting and UVP significantly a...

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Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Surface characteristics and bioactivity of zirconia (Y-TZP) with different surface treatments

et al. 2020

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Polycrystalline particulates synthesized on zirconia for enhanced bioactivity: An in vitro study

2022

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Zirconia is a promising material for dental implant with its excellent biocompatibility, good mechanical properties, and esthetic effect similar to natural teeth. To improve the bioactivity and osteogenic properties of zirconia, pre-sintered zirconia discs were divided into C, T 3 , T 5 , and T 7 group. Group C was as control. T 3 , T 5 , and T 7 groups were soaked in hydrofluoric acid (HF) for 30, 50, and 70 s, respectively. Then, they were placed into CaCl 2 solution and heated in NaOH solution. After sintering, the samples were characterized by scanning electron microscopy, energy dispersive spectrometry, and X-ray diffraction, which confirmed the ZrO 2 polycrystalline particulates in situ synthesized on the treated sample discs. The surface roughness of the treated samples was increased with the prolonged of acid treatment time (p < .05), while the three-point bending strength did not decrease significantly (p > .05). MC3T3-E1 cells were cultured on zirconia discs to evaluate the bioactivity and osteogenic effect of modified zirconia. The living&dead fluorescence staining and CCK-8 assay showed that the specimens were non-toxic and significantly promoted cell proliferation. In addition, the cell proliferation was enhanced with the increase of zirconia surface roughness. Polycrystalline particles modified zirconia were beneficial to cell spreading. After osteogenic induction, MC3T3-E1 cells inoculated on modified zirconia exhibited higher alkaline phosphatase activity, mineralization activity and upregulated osteogenesis-related gene expression. Above all, in situ synthesized polycrystalline particulates significantly improve the biological activity of zirconia, which will promote the widespread application of zirconia implants.bioactivity, in situ synthesized, osteogenesis, polycrystalline particulates, zirconia | INTRODUCTIONWith the development of dental materials and the increasing awareness of dental health, implantation has become the main choice for patients subjected to dentition defects and dentition loss. [1][2][3][4] Although titanium and titanium alloy have long been the dominant implant materials, they still have a series of problems, such as the gray color reducing esthetic outcomes, 5 hypersensitivity caused by Ti ion precipitation 6 and the corrosion occurring in saliva. 7 Zirconia with its excellent biocompatibility, desirable esthetics characteristic, and durable corrosion resistance is the most promising alternative material for titanium and titanium alloy implants. 8-11 However, zirconia is considered to be an inert biomaterial and its osteogenic effect needs to be improved to promote its wide application in the field of dentistry. 12,13 For successful long-term treatment of zirconia implants, modifications have been proposed to alter the surface chemistry, morphology, and bioactivity, as is widely used in Ti implants. [14][15][16][17] Many studies have focused on zirconia surface modifications to improve its

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New Trends in Glass Matting Technologies

et al. 2023

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Evaluation of Sandblasting on Mechanical Properties and Cell Response of Bioactive Glass Infiltrated Zirconia

Cited by 9 publications

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Surface characteristics and bioactivity of zirconia (Y-TZP) with different surface treatments

Surface characteristics and bioactivity of zirconia (Y-TZP) with different surface treatments

Polycrystalline particulates synthesized on zirconia for enhanced bioactivity: An in vitro study

New Trends in Glass Matting Technologies

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