Evaluation of Risk Parameters in Bone Regeneration Using a Customized Titanium Mesh

Hartmann, Amely; Hildebrandt, H; Schmohl, Jörg U; Kämmerer, Peer W.

doi:10.1097/id.0000000000000933

Cited by 35 publications

(54 citation statements)

References 41 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…This study shows that treatment with customized titanium meshes offers the opportunity to provide highquality work in large three-dimensional bony defects. The benefits like precise fit, shorter time of surgery, predictable outcome and good acceptance of the surgical procedure were already described in recent literature [27,28]. Although exposures are a common complication associated with titanium mesh technique, grafting outcome was not affected.…”

Section: Discussionmentioning

confidence: 83%

“…These different results may be caused by a lack in literature to precisely describe the exposures according to size. By distinguishing in severity of the exposure [27], we were able to show that most of them are only slight and only punctual. Another point is the various titanium mesh techniques, various surgical protocols and skills.…”

Section: Discussionmentioning

confidence: 92%

“…Exposures of the titanium mesh were classified concerning their size. "A" was a punctual exposure, "B" an exposure like one premolar size and "C" a complete one whereas "D" was no exposure [27]. Mesh size was defined according to the missing teeth.…”

Section: Outcome Assessmentmentioning

confidence: 99%

See 2 more Smart Citations

Minimizing risk of customized titanium mesh exposures – a retrospective analysis

Hartmann

Seiler

2020

BMC Oral Health

Self Cite

View full text Add to dashboard Cite

Background: Recommendations for soft tissue management associated with customized bone regeneration should be developed. The aim of this study was to evaluate a new protocol for customized bone augmentation in a digital workflow. Methods: The investigators implemented a treatment of three-dimensional bone defects based on a customized titanium mesh (Yxoss CBR®, ReOSS, Filderstadt, Germany). Patients and augmentation sites were retrospectively analysed focussing on defect regions, demographic factors, healing difficulties and potential risk factors. An exposure rate was investigated concerning surgical splint application, A®-PRF and flap design. Results: In total, 98 implants could be placed. Yxoss CBR® was removed after mean time of 6.53 ± 2.7 months. Flap design was performed as full flap preparation (27.9%), full flap and periosteal incision (39.7%), periosteal incision (1.5%), poncho/split flap (27.9%) and rotation flap (2.9%). In 25% of the cases, exposures of the meshes were documented. Within this exposure rate, most of them were slight and only punctual (A = 16.2%), like one tooth width (B = 1.5%) and complete (C = 7.4%). A®-PRF provided significantly less exposures of the titanium meshes (76.5% no exposure vs. 23.5% yes, p = 0.029). Other parameters like tobacco abuse (p = 0.669), diabetes (p = 0.568) or surgical parameters (mesh size, defect region, flap design) did not influence the exposure rate. Surgical splints were not evaluated to reduce the exposure rate (p = 0.239). Gender (female) was significantly associated with less exposure rate (78,4% female vs. 21.6% male, p = 0.043). Conclusions: The results of this study suggest that the new digital protocol including patient-specific titanium meshes, resorbable membranes and bone grafting materials was proven to be a promising technique. To improve soft tissue healing, especially A®-PRF should be recommended.

show abstract

Section: Discussionmentioning

confidence: 83%

Section: Discussionmentioning

confidence: 92%

See 1 more Smart Citation

Minimizing risk of customized titanium mesh exposures – a retrospective analysis

Hartmann

Seiler

2020

BMC Oral Health

Self Cite

View full text Add to dashboard Cite

show abstract

“…Research and industry concerns lie in determining where AM can substitute or generate new manufacturing systems. [53][54][55] AM technologies have been selected to manufacture Ti implants, customized subperiosteal Ti implants, [82][83][84][85][86] customized AM Ti meshes for bone grafting techniques, [87][88][89][90][91][92][93][94][95] Co-Co frameworks for implant impression procedures, 96,97 and Co-Cr and Ti implant frameworks for implant-supported prostheses. [98][99][100][101][102] With the introduction of AM technologies, different studies have analyzed the potential to manufacture Ti AM dental implants (Table 1), [55][56][57][58][59][60][61][62][63][64][65][66][67][68][69][70][71][72][73] customized designs that replicate the tooth's root shape (Table 2), [74]…”

Section: Application Of Am Technologies In Implant Dentistrymentioning

confidence: 99%

A Review of the Applications of Additive Manufacturing Technologies Used to Fabricate Metals in Implant Dentistry

Revilla‐León

Sadeghpour²,

Özcan

2020

Journal of Prosthodontics

View full text Add to dashboard Cite

Purpose To review the primary additive manufacturing (AM) technologies used to fabricate metals in implant dentistry and compare them to conventional casting and subtractive methods. Methods The literature on metal AM technologies was reviewed, and the AM procedures and their current applications in implant dentistry were collated and described. Collection of published articles about metal AM in dental field data sources: MEDLINE, EMBASE, EBSCO, and Web of Science searched. All studies related to AM technology description, analysis, and evaluation of applications in implant dentistry, including AM titanium (Ti) dental implants, customized Ti mesh for bone grafting techniques, cobalt‐chromium (Co‐Cr) frameworks for implant impression procedures, and Co‐Cr and Ti frameworks for dental implant‐supported prostheses were reviewed. Results Literature has demonstrated the potential of AM technologies to fabricate dental implants, root‐analog implants, and functionally graded implants; as well as the ability to fabricate customized meshes for bone grafting procedures. Metal AM technologies provide a reliable method to manufacture frameworks for implant impression procedures. Co‐Cr and Ti AM frameworks for implant‐supported prostheses provide a clinically acceptable discrepancy at the implant‐prostheses interface. Conclusions Additional clinical studies are required to assess the long‐term clinical performance, biological and mechanical complications, and prosthetic restoration capabilities of additively manufactured dental implants. Moreover, further studies are needed to evaluate their long‐term success and survival rates and biological and mechanical complications of AM implant‐supported prostheses.

show abstract

“…Non-resorbable systems include titanium meshs and polytetra uoroethylene membranes. Those materials have to be removed in a second procedure after completion of the regenerative bone healing [4], whereas absorbable membranes are dissolved by catalytic processes [2,5]. These membranes mostly consist of porcine or bovine collagen and are characterized by a good barrier function [3,6].…”

Section: Introductionmentioning

confidence: 99%

A Collagen Membrane Influences Bone Turnover Marker in Vivo After Bone Augmentation With Xenogenic Bone

Staedt

Dau

Schiegnitz

et al. 2020

Preprint

View full text Add to dashboard Cite

Background:The aim was to compare early biochemical and histological osseous healing of chronic mandibular defects regenerated with bovine bone substitute with and without collagen membranein vivo. Methods:Eight weeks after formation of a lateral defect in the mandible of 40 rabbits, bovine bone substitute with (“+”;n=20) and without (“-“;n=20) collagen membrane was applied. Blood and bone was collected 24, 72 hours, 7, 14 and 21 days after surgery. Total acid phosphatase, bone acid phosphatase, total alkaline phosphatase and bone alkaline phosphatase activities were compared between groups. Formation of new bone was quantified histologically for all time points.Results:24 hours after surgery, bone alkaline phosphatase was significantly elevated in “+” group when compared to “-“ (p=0.012). After 72 hours, all bone turnover markers except for total acid phosphatase (p=0.078) where significantly elevated in “+” (all p<0.05). 14 days after surgery, the significant highest values for all bone turnover markers were detected in “-“ (all p<0.05). A significant difference in favor of group “-“ could also be detected after 3 weeks in terms of both acid phosphatases (p<0.05). In histology, no significant differences could be detected.Conclusion: Bone regeneration with bovine bone substitute material and collagen membrane shows a significantly earlier bone remodeling activity but does not seem to influence formation of new bone in histological samples.

show abstract

Evaluation of Risk Parameters in Bone Regeneration Using a Customized Titanium Mesh

Cited by 35 publications

References 41 publications

Minimizing risk of customized titanium mesh exposures – a retrospective analysis

Minimizing risk of customized titanium mesh exposures – a retrospective analysis

A Review of the Applications of Additive Manufacturing Technologies Used to Fabricate Metals in Implant Dentistry

A Collagen Membrane Influences Bone Turnover Marker in Vivo After Bone Augmentation With Xenogenic Bone

Contact Info

Product

Resources

About