Evaluation Of Risk Factors For Respiratory Complications After Lung Resection

Abstract

Objectives: Respiratory complications are an important contributor to morbidity and mortality following lung resection. The surgical techniques used and the patient's pre-operative medical condition determine the severity of complications. The aim of this study is to evaluate the relationship between the perioperative characteristics of patients undergoing lung resection and the development of pulmonary complications (PC). Methods: We retrospectively reviewed the records of 1186 patients who underwent lung resections between 2017 and 2020 and identified 124 patients who developed PC. A group of 215 consecutive patients who underwent surgery during the same period and did not develop complications were included as the control group. The groups were compared to evaluate risk factors for PC. Results:The patients had a mean age of 58.9±12.1 (range, 18-83) years and 82% were men (n=278). Factors significantly associated with PC were age over 65 years, male sex, presence of chronic heart failure, coronary artery disease, and chronic obstructive pulmonary disease, undergoing pneumonectomy, intraoperative use of blood products, reoperation due to bleeding, operative time longer than 4 h, and intraoperative inotrope use. Independent variables for PC were intraoperative inotrope use, preoperative anticoagulant use, revision due to hemorrhage, high Sequential Organ Failure Assessment (SOFA) score, low Forced Expiratory Volume in the 1 st s (FEV1), and low preoperative hemoglobin values. Conclusion:This study demonstrated the presence of many risk factors for PC after lung resection. In our study, independent risk factors for PC; intraoperative inotropic use, preoperative anticoagulant use, revision due to bleeding, high SOFA score, low FEV1, and low preoperative hemoglobin values were observed.