Evaluation of revascularization after total arch replacement in common carotid artery occlusion

Matsuda, Yasuhiro; Koyama, Tadaaki

doi:10.12998/wjcc.v6.i1.6

Cited by 2 publications

(1 citation statement)

References 11 publications

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“…Since the subclavian artery had severe stenosis, it was not used as an inflow vessel. [ 11 ] In fact, the patient’s left vertebral artery was so robust that a left V3-radial artery graft-left M2 bypass might have been a potential treatment option; however, because of the severe stenosis in the left subclavian artery, there was uncertainty regarding sufficient blood supply. Therefore, we had to select a carotid-to-carotid crossover bypass.…”

Section: Discussionmentioning

confidence: 99%

A case of symptomatic carotid artery occlusion after aortic arch replacement treated with carotid-carotid crossover bypass

Sakamoto

MAEDA

Takemoto

et al. 2022

Surgical Neurology International

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Background: Symptomatic common carotid artery (CCA) occlusion is rare and its treatment remains unestablished. Although cases of subclavian-to-carotid bypass have been reported, very few cases of carotid-tocarotid crossover bypass have been reported, despite its advantages. We report a case of Riles type 1A symptomatic CCA occlusion after aortic arch replacement that was treated with carotid-to-carotid crossover bypass with favorable outcomes. Case Description: A 65-year-old woman with a history of hypertension, hyperlipidemia, diabetes, and total arch replacement for thoracic aortic aneurysm was admitted to our hospital with a complaint of the right hemiparesis and motor aphasia. Head magnetic resonance imaging revealed a fresh infarction in the left cerebral hemisphere. Cervical computed tomography (CT) angiography revealed left CCA occlusion. Thoracic CT angiography showed severe stenosis of the left subclavian artery. SPECT showed a general decrease in blood flow in the left cerebral hemisphere. We performed a carotid-to-carotid crossover bypass with a synthetic graft that was passed through the subcutaneous tunnel. First, the right carotid artery-synthetic graft end-to-side anastomosis was performed. Subsequently, we performed synthetic graft-left CCA end-to-side anastomosis. The postoperative course was uneventful. Cervical computed tomography angiography showed perfect patency of the crossover bypass. The patient recovered almost completely and was independently performing daily activities. Conclusion: Carotid-to-carotid crossover bypass is a durable treatment for symptomatic CCA occlusion. Further studies are needed to compare its outcomes with those of other methods and to confirm our findings with larger sample size.

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Section: Discussionmentioning

confidence: 99%

A case of symptomatic carotid artery occlusion after aortic arch replacement treated with carotid-carotid crossover bypass

Sakamoto

MAEDA

Takemoto

et al. 2022

Surgical Neurology International

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The E2F family as potential biomarkers and therapeutic targets in colon cancer

Yao

Shao

2020

PeerJ

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Background The E2F family is a group of genes encoding a series of transcription factors in higher eukaryotes and participating in the regulation of cell cycle and DNA synthesis in mammals. This study was designed to investigate the role of E2F family in colon cancer. Methods In this study, the transcriptional levels of E2F1-8 in patients with colon cancer from GEPIA was examined. Meanwhile, the immunohistochemical data of the eight genes were also obtained in the The Human Protein Atlas website. Additionally, we re-identified the mRNA expression levels of these genes via real time PCR. Furthermore, the association between the levels of E2F family and stage plot as wells overall survival of patients with colon cancer were analyzed. Results We found that the mRNA and protein levels of E2F1, E2F2, E3F3, E2F5, E2F7 and E2F8 were significantly higher in colon cancer tissues than in normal colon tissues while the expression levels of E2F4 and E2F6 displayed no significant difference between colon cancer tissues and normal tissues. Additionally, E2F3, E2F4, E2F7 and E2F8 were significantly associated with the stages of colon cancer. The Kaplan-Meier Plotter showed that the high levels of E2F3 conferred a worse overall survival and disease free survival of patients with colon cancer. Also, high levels of E2F4 resulted in a worse overall survival. Conclusion Our study implied that E2F3, E2F4, E2F7 and E2F8 are potential targets of precision therapy for patients with colon cancer while E2F1, E2F2, E3F3, E2F5, E2F7 and E2F8 are potential biomarkers for the diagnosis of colon cancer.

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Evaluation of revascularization after total arch replacement in common carotid artery occlusion

Cited by 2 publications

References 11 publications

A case of symptomatic carotid artery occlusion after aortic arch replacement treated with carotid-carotid crossover bypass

A case of symptomatic carotid artery occlusion after aortic arch replacement treated with carotid-carotid crossover bypass

The E2F family as potential biomarkers and therapeutic targets in colon cancer

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