Evaluation of red cell distribution width in the diagnosis of iron deficiency anemia

Sharma, Abhishek; Sharma, Mahima; Sharma, Vandana

doi:10.18203/2320-6012.ijrms20162603

Cited by 10 publications

(13 citation statements)

References 6 publications

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“…Similarly, the RDW sensitivity of 78% is also in keeping with previous studies. 19,24,25 A previous study by Nesa et al 26 reported RDW specificity of 17.50% that is contrary to present and previous studies. 1,24,25 Raised RDW in iron deficiency anemia is also reported by Suri et a 27 and Choudhary et al 28 who reported a sensitivity and specificity of 90% and 51%, 94% and 59% and 91.30%and 43.47% respectively.…”

Section: Discussioncontrasting

confidence: 83%

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Iron Deficiency Anemia

Maheshwari

Khemani

Hingorjo

et al. 2018

TPMJ

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To evaluate the predictive value of Red blood cell distribution width (RDW) for the iron deficiency anemia in children. Study Design: Cross sectional study. Place and Duration: Department of Paediatrics, Layari General Hospital Shaheed Muhtrama Benazir Bhutto Medical College from December 2015 to March 2016. Methodology: A sample of 100 children (53 male and 47 female) was selected through non-probability (purposive sampling). 5 ml venous blood was collected, 3 ml was shifted to EDTA containing vacutainers and remaining was processed and centrifuged to separate sera. Complete blood counts and iron profile were performed. Data of cases and controls was analyzed on Statistix 10.0 software (USA) (P ≤0.05). Results: Severe iron deficiency and iron deficiency anemia were noted. Serum Iron, TIBC and Ferritin were noted as 63.49±32.94 and 76.06±40.38 μg/dl, 468.7±142.2 and 445.5±135.2 μg/ dl, & 36.2±14.12 and 43.2±13.5 ng/dl respectively. RDW proved a sensitivity and specificity of 78% and 56% respectively (0.001). Conclusion: We observed severe iron deficiency anemia in children and Red blood cell distribution width showed high sensivity in predicting iron deficiency anemia.

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Section: Discussioncontrasting

confidence: 83%

“…20,21 from developing countries. [19][20][21] With the advent of automated analyzers, red blood cell (RBC) indices have emerged as low cost parameters for early detection of anemias. 22 RDW has emerged as a better RBC index to differentiate iron deficiency anemia from other causes of microcytosis especially thalassemia trait.…”

Section: Discussionmentioning

confidence: 99%

Iron Deficiency Anemia

Maheshwari

Khemani

Hingorjo

et al. 2018

TPMJ

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“…The discriminating function of the various indices is dependent on the age of a patient. It has been observed that the most accurate discriminant index for the patients younger than 10 years is total RBC count and for those older than ten years are TRBC and RDWI 23,24. In a recent study another discriminating index, Matos & Carvalho Index has been mentioned as a very effective discriminating factor in the differentiation of IDA and βTT.…”

Section: Discussionmentioning

confidence: 99%

Differentiation of beta thalassemia trait from iron deficiency anemia by hematological indices

Jameel¹,

Baig

Ahmed³

et al. 2017

Pak J Med Sci

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Objective:We aimed at finding out reliable parameter in the differentiation of iron deficiency anemia (IDA) and beta-thalassemia trait (β-TT) in the adult population subjected to Saudi Arabian Premarital Screening Program.Methods:A total of 620 adults (age range 21-36 years) reported during February 2012 to November 2012. Tests for serum iron and ferritin were carried out in individuals showing low hemoglobin (Hb). All the selected subjects’ samples were subjected to blood morphology, comparison of MCV, RBC count. Red Cell Distribution Width (RDW) was noted from the Coulter Report whereas Red Cell Distribution Width Index (RDWI) value was calculated for all the samples.Results:A total of one hundred &thirty-five individuals with hypochromic microcytic anemia having normal hemoglobin F and hemoglobin A2 < 3.2% were inducted in the study. Ninety-three were diagnosed having IDA, whereas thirty-two were having βTT. Ten individuals revealed other causes of anemia. The RBC count was higher, and MCV was much lower in βTT as compared to IDA. Both groups were subjected to RDW and RDWI, however, RDWI which showed better sensitivity and specificity for βTT.Conclusion:RDWI is a reliable and useful index for differentiation among IDA and βTT, as compared to RDW.

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“…The findings are in agreement with previous studies. 17,18 A recent study 19 reported similar age findings in male population. Of 100 study subjects, 53% were male and 47% were female, this is in accordance to recent study.…”

Section: Discussionmentioning

confidence: 53%

“…Of 100 study subjects, 53% were male and 47% were female, this is in accordance to recent study. Sharma et al 19 has reported more female compared to male i.e. 62% versus 38%.…”

Section: Discussionmentioning

confidence: 95%

Iron Deficiency Anemia

Maheshwari

Khemani

Hingorjo

et al. 2018

TPMJ

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Objectives: To evaluate the predictive value of Red blood cell distribution width(RDW) for the iron deficiency anemia in children. Study Design: Cross sectional study. Placeand Duration: Department of Paediatrics, Layari General Hospital Shaheed Muhtrama BenazirBhutto Medical College from December 2015 to March 2016. Methodology: A sample of 100children (53 male and 47 female) was selected through non- probability (purposive sampling). 5ml venous blood was collected, 3 ml was shifted to EDTA containing vacutainers and remainingwas processed and centrifuged to separate sera. Complete blood counts and iron profile wereperformed. Data of cases and controls was analyzed on Statistix 10.0 software (USA) (P ≤0.05).Results: Severe iron deficiency and iron deficiency anemia were noted. Serum Iron, TIBC andFerritin were noted as 63.49±32.94 and 76.06±40.38 μg/dl, 468.7±142.2 and 445.5±135.2 μg/dl, & 36.2±14.12 and 43.2±13.5 ng/dl respectively. RDW proved a sensitivity and specificity of78% and 56% respectively (0.001). Conclusion: We observed severe iron deficiency anemia inchildren and Red blood cell distribution width showed high sensivity in predicting iron deficiencyanemia.

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Evaluation of red cell distribution width in the diagnosis of iron deficiency anemia

Cited by 10 publications

References 6 publications

Iron Deficiency Anemia

Iron Deficiency Anemia

Differentiation of beta thalassemia trait from iron deficiency anemia by hematological indices

Iron Deficiency Anemia

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