Evaluation of Rdw, Mpv, Platelet Laboratory Parameters in Prostate Cancer Patients Admitting to Emergency Department With Hematuria

Abstract

Abstract:Prostate Cancer (PCA) is the most common among urological malignant tumors. Prostate cancer patients may be unable to urinate, and may have hospital admissions with symptoms like erectile dysfunction or hematuria. Although hematuria is a highly common clinical manifestation in the society, the frequency of it is not known in prostate cancer patients, which is one of the urological malignancies. The purpose of this study was to investigate the relation of RDW (distribution width of the red blood cells), MPV (mean platelet volüme) and Platelet Blood Parameters with hematuria in prostate cancer patients admitting to the emergency clinic with hematuria. The present study was conducted retrospectively by examining the hospital automation system and patient files of prostate cancer patients admitting with hematuria between 01.01.2018-01.01.2020 to Yozgat Bozok University Emergency Medical Clinic. A total of 60 patients with full files and that matched study criteria were included in the study. For the purpose of comparing blood parameters for the purpose of comparing blood parameters, 45 patients with prostate cancer, nonspecific complaints and non-additional diseases were evaluated as the control group. MPV (mean platelet volume), RDW-CV (red blood cells distribution width) blood parameters of patients with prostate cancer hematuria were found to be significantly higher in the control group. Platelet value of the patient group was found to be significantly lower than the control group. However, the platelet blood parameter values were significantly lower in patients with major hematuria than in patients with minor hematuria (<0.05). According to the results of the present study, we believe that all the three parameters (RDW, MPV and Platelet levels), which can be measured in full blood count in the prostate cancer patient group in particular, can guide clinicians that the finding of hematuria can develop, and will be beneficial in follow-up and treatment. However, unlike RDW and MPV laboratory parameters, we think the Platelet parameter is an important parameter in predicting the type of hematuria that can develop.