Evaluation of quality of life in fertile Turkish women with severe endometriosis

Abstract

We assessed the impact of pain, dysmenorrhoea and dyspareunia on the quality of life among Turkish fertile women with severe endometriosis. A total of 33 patients with histopathologically diagnosed severe endometriosis (Stage IV, revised criteria of the American Fertility Society (rAFS score) were enrolled into the study. Patients reported chronic pelvic pain using a visual analogue scale (VAS) and severity of dysmenorrhoea, dyspareunia and pelvic tenderness using the verbal rating scale (VRS). Quality of life (physical, psychological, social, environmental domains) was evaluated using the World Health Organization Quality of Life Assessment-BREF (WHOQOL-BREF). There were no correlations between quality of life and VRS and VAS scores of chronic pelvic pain in patients with dyspareunia (p > 0.05). VRS in patients with dysmenorrhoea negatively correlated with physical, social and environmental dimensions of quality of life (r = -0.382, r = -0.221, r = -0.373 and p = 0.028, p = 0.013, p = 0.033, respectively). Although the severity of dysmenorrhoea seems to be related with lower quality of life, chronic pelvic pain and dyspareunia due to endometriosis may not have any deleterious effects on the quality of life.

A prospective, single-centre, single-arm, open label study of the long term use of a gonadotropin releasing hormone agonist (Triptorelin SR, 11.25 mg) in combination with Tibolone add-back therapy in the management of chronic cyclical pelvic pain

“…The first result of this study was that there was a significant improvement in pain related QoL parameters that continued throughout the duration of the study but significantly deteriorated after cessation of the medication. The effects of CCPP and endometriosis on QoL have been reported in many previous studies [26][27][28][29][30].…”

Health-related quality of life (Nottingham Health Profile) in patients with endometriomas: correlation with clinical variables and self-reported limitations

“…Women with endometriosis adapt to the disease, which allows them to function in good relationships with people in the immediate environment, implement plans and feel great satisfaction with life [28]. This was directly measured by Kiykac Altinbas et al [29], where the severity of dysmenorrhea was related with quality of life; it was found that chronic pelvic pain and dyspareunia failed to show a negative effect on QoL. The results are also of importance because of the careful selection of the most advanced stages of endometriosis [29].…”

Endometriosis-related infertility: assisted reproductive technology has no adverse impact on pain or quality-of-life scores

“…Endometriosis-related pain symptoms during ART might be modulated by other factors, such as the endometriosis phenotype (SUP, OMA, or DIE) or the intensity of ovarian response during COS. Moreover, it is known that endometriosis-related pain symptoms have a negative impact on patients' well-being (18); however, the QoL of infertile women with endometriosis undergoing ART has not yet been evaluated.…”