Evaluation of Quality of Life in HIV-Infected Children and Children with Cancer

Leao, Ana Karla Buczynski Anna Thereza Thome

doi:10.4172/2161-1122.1000276

Cited by 2 publications

(2 citation statements)

References 27 publications

(41 reference statements)

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“…ART has been reported to be effective in improving the HRQOL by improving the immune status of the patients. 5,18,28 Baneerjee et al in India and Kuntawee et al in Thailand reported that antiretroviral treatment may be associated with improved quality of life among HIV-infected children. 8,5 Better quality of life is an important indicator of treatment efficacy.…”

Section: Discussionmentioning

confidence: 99%

Health-related quality of life of HIV-infected children in Uyo. Akwa Ibom State, Nigeria

2023

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Background: HIV-infected children are surviving into adolescence and adulthood due to the effectiveness of highly active antiretroviral therapy (HAART) but they now have to cope with living with a chronic disease. Health-related quality of life (HRQOL) has been shown to be an invaluable tool in assessing health outcome in chronic health conditions including HIV. Little is known about the HRQOL of HIV-infected children in both developing and developed countries. The study aimed at assessing the HRQOL of Nigerian children with HIV infection and compare it with that of healthy children in Uyo. Methods: A cross-sectional study of 211 HIV-infected children aged 2 to 15 years and 211 age, sex and social class-matched HIV-uninfected children with their caregivers was conducted at the University of Uyo Teaching Hospital, Uyo for a duration of nine months from October 2016 to July 2017. A generic version of the Pediatric Quality of Life Inventory (PedsQL 4.0) was used to measure their HRQOL. Results: From both self and proxy reports, there was no significant difference in the mean total HRQOL score of HIV-infected children and that of HIV-uninfected children. Conclusions: HRQOL of HIV-infected children in Uyo, Akwa Ibom state was good and comparable to that of HIV-uninfected children. Assessment of HRQOL should be incorporated into routine antiretroviral therapy ART programmes as a measure of the outcome of disease management. This will further help to identify needs and direct interventions for holistic care of these vulnerable children.

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Section: Discussionmentioning

confidence: 99%

Health-related quality of life of HIV-infected children in Uyo. Akwa Ibom State, Nigeria

2023

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“…Oral conditions affect OHRQoL through interference with daily activities such as chewing, swallowing, speaking, sleeping, choosing what to eat, schooling social interaction, and more [ 4 ]. Poor oral health negatively affects the quality of life generally [ 5 ], and especially among people with other chronic diseases such HIV-infection [ 9 ]. For example, pain and discomfort caused by dental caries and periodontal diseases an interfere with nutritional intake among PLHIV and, therefore, can affect their immunity and general well-being [ 10 ].…”

Section: Introductionmentioning

confidence: 99%

Oral health-related quality of life among people living with HIV and HIV-negative adults in Kigali, Rwanda: a comparative cross-sectional study

Murererehe,

Malele-Kolisa,

Niragire

et al. 2024

BMC Oral Health

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Background Assessing health-related quality of life has become integral to people living with HIV (PLHIV) follow-up. However, there is a lack of data regarding the impact of oral health on quality of life, known as Oral health-related quality of life (OHRQoL) among PLHIV compared to HIV-negative individuals in Rwanda. Aim The study aimed to assess OHRQoL among PLHIV compared to HIV-negative counterparts in Kigali, Rwanda. Methods The Oral Health Impact Profile short version (OHIP-14) questionnaire was interviewer-administered to 200 PLHIV and 200 HIV-negative adults (≥ 18 years old) at an HIV clinic of Kigali Teaching Hospital (CHUK). Socio-demographic characteristics, including age, sex, occupation, and socioeconomic status (SES) of participants, were collected using a survey questionnaire. A 4-point Likert scale was used to assess the frequency of oral impacts for all 14 items within 7 domains of the OHIP tool. The descriptive statistics were used to see frequencies and percentages of OHRQoL among PLHIV and HIV-negative persons, respectively. The Chi-square test was used to determine the association of OHRQoL with caries (DMFT) and periodontal disease (CPITN) among PLHIV compared to HIV-negative individuals. Results The results revealed a higher prevalence of PLHIV with poor OHRQoL than HIV-negative individuals in 5 domains and almost all items of OHIP-14 except for the OHIP 3 (found it uncomfortable to eat any foods because of problems with teeth or mouth) and OHIP-14 (being totally unable to function because of problems with teeth or mouth). The findings showed statistically significant results (p ≤ 0.05) for the OHIP1 item “trouble pronouncing any word,” with a prevalence of 2.5% (n = 11) and 2.25% (n = 9) in PLHIV and HIV-negative, respectively. Also, PLHIV had a significantly higher prevalence, 2.75% (n = 11) for the OHIP 13 item “life not satisfying due to teeth and mouth problems compared to HIV-negative individuals 2% (8) p ≤ 0.05. Moreover, dental caries was significantly associated with poor OHRQoL among PLHIV and HIV-negative adults and for all 14 items of the OHIP tool. Periodontal disease was not significantly associated with OHRQoL among PLHIV and HIV-negative adults. Conclusion This study revealed poor OHRQoL among PLHIV compared to HIV-negative adults. There is a need for further longitudinal studies to investigate the OHRQoL in Rwanda, especially among PLHIV. It is essential to include oral health care as one of the components of the medical health care programs for PLHIV in Rwanda.

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Evaluation of Quality of Life in HIV-Infected Children and Children with Cancer

Cited by 2 publications

References 27 publications

Health-related quality of life of HIV-infected children in Uyo. Akwa Ibom State, Nigeria

Health-related quality of life of HIV-infected children in Uyo. Akwa Ibom State, Nigeria

Oral health-related quality of life among people living with HIV and HIV-negative adults in Kigali, Rwanda: a comparative cross-sectional study

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