Evaluation of Pulmonary Function in Adults with Grade III Obesity

Abstract

Pulmonary function studies in obese individuals have alerted the pathophysiological changes due to weight gain. However, these changes are not fully explained yet. Objective: To evaluate and analyze the pulmonary function of obese adults in the city of Manaus (AM, Brazil) and to correlate the parameters of spirometry with weight and BMI. Method: A descriptive cross-sectional study, in which pulmonary function of 22 adults with grade III obesity was evaluated pre and post bronchodilator administration, performed at the Adriano Jorge Hospital Foundation-FHAJ. Results: Of the 22 patients evaluated, 6 were male and 16 were female; mean age was 37.1 ± 7.4 years, with a weight of 134.2 ± 28.6 kg and a BMI of 51.1 ± 9.4 kg/m 2 , corresponding to grade III obesity. Spirometry showed a reduction in values obtained from Forced Vital Capacity (FVC), Forced Expiratory Volume in the first second (FEV1) and Peak Expiratory Flow (PEF) in relation to those predicted, with 23% of restrictive disorders. There were negative correlations between BMI and PEF, weight and FVC, weight and PEF. The P value for correlation of weight and FEV1 is not statistically significant. Conclusion: Restrictive and obstructive disorders are prevalent in the population with grade III obesity. Correlations between pulmonary function and BMI/weight were negative for this specific population.

Pressões respiratórias máximas em indivíduos obesos antes e após cirurgia bariátrica

“…A obesidade, considerada um importante problema de saúde pública global, é definida como uma doença crônica, multifatorial, não transmissível e não infecciosa [1,2]. É uma síndrome inflamatória caracterizada pelo acúmulo excessivo de tecido adiposo capaz de gerar alterações sistêmicas, decorrentes da interação entre fatores genéticos, ambientais, emocionais e estilo de vida [1][2][3][4][5].…”