Evaluation of prostate-specific antigen testing: An empirical survey of laboratories in Nigerian tertiary care centers

Meka, IjeomaA; Okwor, ChikaJ; Arum, EkeneJ; Ogamba, MichaelI; Omotowo, BabatundeI; Kanu, OkezieO

doi:10.4103/ijmh.ijmh_8_22

Cited by 1 publication

(1 citation statement)

References 13 publications

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“…Assays used for testing to detect prostate cancer are highly variable in quality in SSA, as is quality control in clinical laboratories, particularly in private laboratories. PSA testing may be costly as well [12]. Biopsies are the gold standard for diagnosing prostate cancer, but they are often not possible because of the cost and limitations in urology (ultrasound-guided biopsies) and biopsy pathology services [13], particularly in rural areas where 50% of the population live [14].…”

Section: Obstacles To Detection Diagnosis and Treatment Of Prostate C...mentioning

confidence: 99%

Potential New Approaches for Prostate Cancer Management in Resource-Limited Countries in Africa

Bosland

Shittu

Ikpi

et al. 2023

Annals of Global Health

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Prostate cancer is a major male malignancy in many sub-Saharan countries in Africa. Because of resource limitations, screening, early detection, diagnosis, and curative treatments are not available for many men on the subcontinent, and there are even barriers to the treatment of advanced-stage metastatic prostate cancer. We are making the case for new approaches to the detection, diagnosis, and treatment of this malignancy in sub-Saharan Africa and other low-resource regions-approaches that differ from the ones available and used in high-income countries. The development of one-step dipstick-type detection assays of serum prostate-specific antigen (PSA) offers an approach to prostate cancer detection, treatment and monitoring that circumvents issues related to laboratory quality control and is also low-cost. Curative-intent treatments of early-stage prostate cancer are often unavailable in low-resource contexts, and most prostate cancers are not detected in Africa until they are at an advanced stage. Hence, androgen deprivation treatments, including orchiectomy and older low-cost drugs, offer feasible and affordable approaches to prolong survival and sustain a reasonable quality of life. However, clinical trials are needed to identify which of these androgen deprivation treatments are most efficacious and best tolerated to make progress in providing medical care for men with prostate cancer in sub-Saharan Africa and other low-and lower-middle-income areas around the world.

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Section: Obstacles To Detection Diagnosis and Treatment Of Prostate C...mentioning

confidence: 99%

Potential New Approaches for Prostate Cancer Management in Resource-Limited Countries in Africa

Bosland

Shittu

Ikpi

et al. 2023

Annals of Global Health

View full text Add to dashboard Cite

show abstract

Evaluation of prostate-specific antigen testing: An empirical survey of laboratories in Nigerian tertiary care centers

Cited by 1 publication

References 13 publications

Potential New Approaches for Prostate Cancer Management in Resource-Limited Countries in Africa

Potential New Approaches for Prostate Cancer Management in Resource-Limited Countries in Africa

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